Chronic cerebrospinal venous insufficiency is not more prevalent in patients with mild multiple sclerosis: a sonographer-blinded, case-control ultrasound study

B Chambers, J Chambers, H Cameron… - Multiple Sclerosis …, 2013 - journals.sagepub.com
Objectives: We designed a prospective case-control study of patients with clinically isolated
syndrome (CIS) and Relapsing–Remitting Multiple Sclerosis (RRMS) with an Expanded …

Chronic cerebrospinal venous insufficiency in multiple sclerosis: A sonographer-blinded case-control study

D Imperiale, F Melis, C Giaccone, M Guido… - Clinical Neurology and …, 2013 - Elsevier
Objectives To evaluate the presence of chronic cerebrospinal venous insufficiency (CCSVI)
and cerebral venous anomalies in a consecutive series of patients with multiple sclerosis …

Chronic cerebrospinal venous insufficiency in multiple sclerosis: a highly prevalent age-dependent phenomenon

R Lanzillo, M Mancini, R Liuzzi, O Di Donato… - BMC neurology, 2013 - Springer
Background This study aimed to investigate the prevalence and clinical relevance of chronic
cerebrospinal venous insufficiency (CCSVI) in multiple sclerosis (MS) patients and healthy …

Evidence against the involvement of chronic cerebrospinal venous abnormalities in multiple sclerosis. A case-control study

IW Rodger, D Dilar, J Dwyer, J Bienenstock, A Coret… - PLoS …, 2013 - journals.plos.org
Objective Multiple sclerosis (MS) is a chronic neurodegenerative disease of the CNS.
Recently a controversial vascular hypothesis for MS, termed chronic cerebrospinal venous …

Chronic cerebrospinal venous insufficiency and venous stenoses in multiple sclerosis

M Blinkenberg, P Åkeson, H Sillesen… - Acta neurologica …, 2012 - Wiley Online Library
Objectives The traditional view that multiple sclerosis (MS) is an autoimmune disease has
recently been challenged by the claim that MS is caused by chronic cerebrospinal venous …

[HTML][HTML] Doppler ultrasound examination of multiple sclerosis patients and control participants: Inter-observer agreement and association with disease

SJ Laukontaus, T Kagayama, M Lepäntalo… - European Journal of …, 2013 - Elsevier
Objective Chronic cerebrospinal venous insufficiency (CCSVI) has been proposed as a
major risk factor for multiple sclerosis (MS). The aim of this study was to assess inter …

Proposed chronic cerebrospinal venous insufficiency criteria do not predict multiple sclerosis risk or severity

D Centonze, R Floris, M Stefanini, S Rossi… - Annals of …, 2011 - Wiley Online Library
Objective: It is still unclear whether chronic cerebrospinal venous insufficiency (CCSVI) is
associated with multiple sclerosis (MS), because substantial methodological differences …

Chronic cerebrospinal venous insufficiency is not associated with multiple sclerosis and its severity: a blind-verified study

MA Leone, O Raymkulova, P Naldi, P Lochner… - PLoS …, 2013 - journals.plos.org
Background Chronic Cerebrospinal Venous Insufficiency (CCSVI) has been associated with
multiple sclerosis (MS) with a risk ranging from as high as two-hundred-fold to a protective …

Extracranial venous hemodynamics in multiple sclerosis: a case-control study

G Tsivgoulis, M Mantatzis, C Bogiatzi, K Vadikolias… - Neurology, 2011 - AAN Enterprises
Objectives: A chronic state of impaired cerebral and cervical venous drainage, termed
chronic cerebrospinal venous insufficiency (CCSVI), has recently been implicated in the …

[HTML][HTML] Screening for chronic cerebrospinal venous insufficiency (CCSVI) using ultrasound. Recommendations for a protocol

AN Nicolaides, S Morovic, E Menegatti… - Functional …, 2011 - ncbi.nlm.nih.gov
Chronic cerebrospinal venous insufficiency (CCSVI) is a syndrome characterized by
stenoses or obstructions of the internal jugular and/or azygos veins with disturbed flow and …