There is clear evidence that the placenta produces leptin. However, it is still unclear to what
extent leptin is released into the maternal and the fetal circulation. The aim of our study was …

The contribution of placental leptin, if any, to both the fetal and maternal circulation and its
role in pregnancy remains to be determined. In an experiment to investigate this, 27 …

Leptin expression in third trimester placenta (p) and leptin concentrations in umbilical cord
blood (cb) were investigated in normal pregnancies [n= 10 (p), 31 (cb)] and abnormal …

Placental tissues from humans, rodents and farm animals contain leptin and its receptor.
Leptin produced by the human placenta has the same size, charge and immunoreactivity as …

There is clear evidence of placental leptin production, as shown recently in trophoblast
cultures and by dual in vitro placenta perfusion (median production of 225 pg/min per g of …

Leptin is a polypeptide hormone originally thought to be produced exclusively by
adipocytes. Recently, however, both leptin messenger ribonucleic acid (mRNA) and leptin …

The mechanisms by which maternal and fetal weight are regulated during pregnancy are
poorly understood. The ob protein, termed leptin, is produced by adipocytes. It is involved in …

Preeclampsia (PE) is a hypertensive disorder, which develops in late pregnancy and is
usually associated with placental hypoxia and dysfunction. We have recently demonstrated …

The gestational profiles of leptin in plasma, adipose tissue and placenta were investigated in
rats. Leptin in plasma and the adipose tissue of the maternal compartment increased as …

Leptin is essential for the establishment of pregnancy and appears to promote fetal growth,
but the mechanisms regulating fetal leptin exposure remain unclear. In rodents, indirect …