Mechanisms and treatment of neuropathic pain

JH Vranken - Central Nervous System Agents in Medicinal …, 2009 - ingentaconnect.com
Neuropathic pain (pain associated with lesions or dysfunction of nervous system) is
relatively common, occurring in about 1% of the population. Studies in animal models …

Elucidation of pathophysiology and treatment of neuropathic pain

JH Vranken - Central Nervous System Agents in Medicinal …, 2012 - ingentaconnect.com
Neuropathic pain, pain arising as a direct consequence of a lesion or disease affecting the
somatosensory system, is relatively common, occurring in about 1% of the population …

Therapeutic targets for the management of peripheral nerve injury-induced neuropathic pain

A Singh Jaggi, N Singh - … Formerly Current Drug Targets-CNS & …, 2011 - ingentaconnect.com
Neuropathic pain is a debilitating form of treatment resistant chronic pain and responds
poorly to the clinically available therapies. Studies from animal models of neuropathic pain …

Drug combinations in the treatment of neuropathic pain

E Eisenberg, E Suzan - Current pain and headache reports, 2014 - Springer
Pharmacotherapy, the main treatment option for neuropathic pain, remains a major clinical
challenge. The most commonly studied drug classes in the context of neuropathic pain …

Neuropathic pain: models and mechanisms

JM Boyce-Rustay, MF Jarvis - Current pharmaceutical design, 2009 - ingentaconnect.com
Advances in the characterization of pain signaling in recent years indicate that distinct
neurophysiological and neurochemical mechanisms contribute to pain arising from injury to …

Pharmacology and treatment of neuropathic pains

TS Jensen, CS Madsen… - Current opinion in …, 2009 - journals.lww.com
Pharmacology and treatment of neuropathic pains : Current Opinion in Neurology
Pharmacology and treatment of neuropathic pains : Current Opinion in Neurology Log in or …

[HTML][HTML] Neuropathic pain; what we know and what we should do about it

PA Smith - Frontiers in Pain Research, 2023 - frontiersin.org
Neuropathic pain can result from injury to, or disease of the nervous system. It is notoriously
difficult to treat. Peripheral nerve injury promotes Schwann cell activation and invasion of …

Translational investigation and treatment of neuropathic pain

B Xu, G Descalzi, HR Ye, M Zhuo… - Molecular …, 2012 - journals.sagepub.com
Neuropathic pain develops from a lesion or disease affecting the somatosensory system.
Translational investigations of neuropathic pain by using different animal models reveal that …

Pharmacotherapy for neuropathic pain

KC Jackson - Pain practice, 2006 - Wiley Online Library
Refractory neuropathic pain can be devastating to a patient's quality of life. Ideally, the
primary goal of therapy would be to prevent the pain, yet even the most appropriate …

Combination pharmacotherapy for neuropathic pain: current evidence and future directions

I Gilron, MB Max - Expert review of neurotherapeutics, 2005 - Taylor & Francis
Current drugs reduce neuropathic pain and improve mood and quality of life. However, as
single agents they are limited by incomplete efficacy and dose-limiting adverse effects …