Critical analysis of empiric antibiotic utilization: establishing benchmarks

JA Claridge, P Pang, WH Leukhardt, JF Golob… - Surgical …, 2010 - liebertpub.com
Aim: We critically evaluated empiric antibiotic practice in the surgical and trauma intensive
care unit (STICU) with three specific objectives:(1) To characterize empiric antibiotics …

Empiric antimicrobial therapy in critical illness: results of a surgical infection society survey

MAW Aarts, J Granton, DJ Cook, JMA Bohnen… - Surgical …, 2007 - liebertpub.com
Background: Antibiotics are prescribed commonly in the intensive care unit (ICU). Often,
therapy is initiated empirically; practice patterns are not well characterized. We documented …

Opportunities to improve antibiotic appropriateness in US ICUs: a multicenter evaluation

KK Trivedi, R Bartash, AR Letourneau… - Critical care …, 2020 - journals.lww.com
Objectives: To use a standardized tool for a multicenter assessment of antibiotic
appropriateness in ICUs and identify local antibiotic stewardship improvement opportunities …

Characteristics of surgical patients receiving inappropriate empiric antimicrobial therapy

SW Davies, JT Efird, CA Guidry, T Hranjec… - Journal of Trauma …, 2014 - journals.lww.com
BACKGROUND Inappropriate antibiotics have been observed to result in an increased
duration of antibiotic treatment and hospital length of stay, development of multidrug …

A complete and multifaceted overview of antibiotic use and infection diagnosis in the intensive care unit: results from a prospective four-year registration

L De Bus, B Gadeyne, J Steen, J Boelens, G Claeys… - Critical Care, 2018 - Springer
Background Preparing an antibiotic stewardship program requires detailed information on
overall antibiotic use, prescription indication and ecology. However, longitudinal data of this …

Antibiotic decision making in surgical intensive care: a qualitative analysis

K Rynkiewich, D Schwartz, S Won, B Stoner - Journal of Hospital Infection, 2020 - Elsevier
Background Antibiotic use in hospitals is high, particularly in surgical specialty and intensive
care units. Antimicrobial stewardship programmes (ASPs) are increasingly intervening in …

[HTML][HTML] When not to start antibiotics: avoiding antibiotic overuse in the intensive care unit

KJ Denny, J De Wale, KB Laupland, PNA Harris… - Clinical Microbiology …, 2020 - Elsevier
Background Most intensive care unit (ICU) patients receive broad-spectrum antibiotics.
While lifesaving in some, in others these treatments may be unnecessary and place patients …

Antibiotic use in the intensive care unit: optimization and de-escalation

M Campion, G Scully - Journal of intensive care medicine, 2018 - journals.sagepub.com
Appropriate antimicrobial therapy is essential to ensuring positive patient outcomes.
Inappropriate or suboptimal utilization of antibiotics can lead to increased length of stay …

Antibiotic use practice and predictors of hospital outcome among patients with systemic bacterial infection: Identifying targets for antibiotic and health care resource …

G Alemkere, A Tenna, E Engidawork - PloS one, 2019 - journals.plos.org
Background Malpractice and excess use of antimicrobials have been associated with
multiple costs, including the development of resistant bacteria, which has become a threat to …

Evaluation of empiric antibiotic use in surgical sepsis

K Fitousis, LJ Moore, J Hall, FA Moore… - The American journal of …, 2010 - Elsevier
BACKGROUND: We performed an evaluation of antimicrobial guidelines for patients with
surgical sepsis. METHODS: The purpose of this study was to validate current empiric …