Background: The long-term significance of early and prolonged antibiotic use in critically ill
patients is yet to be described. Several studies suggest that antimicrobial exposure may …

Empiric antibiotic therapy—the administration of antibiotics before a microbiological
diagnosis of infection is established—is a widely-used, but unproven practice in …

The objectives of the present study were to provide a snapshot analysis of antibiotic
appropriateness in two hospitals in Southern Italy in three specific areas, surgical, medical …

Objective The incidence of inappropriate and excessive empirical antibiotic therapy is
unclear. The aim of this study was to determine the prevalence of different empirical …

BACKGROUND Early appropriate antibiotic therapy is an important component of the
Surviving Sepsis Guidelines bundles that are associated with decreased in-hospital …

Antibiotic resistance is a major health problem and will be probably one of the leading
causes of deaths in the coming years. One of the most effective ways to fight against …

© Journal of Thoracic Disease. All rights reserved. J Thorac Dis 2016; 8 (Suppl 7): S533-
S535 jtd. amegroups. com a significant barrier to antibiotic stewardship in the ICU. Rapid …

Abstract Objectives Emergence of multiresistant Gram-negative organisms in intensive care
units (ICUs) throughout the world is a concerning problem. Therefore we undertook a study …

BACKGROUND: In intensive care unit (ICU) patients, signs of infection and inflammation are
similar, making diagnosis of bacterial infections difficult. Antimicrobials may therefore be …

Objective The purpose of this study was to determine the impact of scheduled changes of
antibiotic classes, used for the empirical treatment of suspected or documented Gram …