The authors developed a simple and sensitive, fully validated HPLC-UV method for the
determination of both 5-FU and its metabolite DHFU in small-volume plasma samples. The …

A relatively simple, sensitive and rapid high-performance liquid chromatographic method is
described for measuring the anticancer drug 5-fluorouracil (5-FU) in human plasma and …

Fluorouracil (5‐Fu) is a commonly used anticancer agent for treatment of solid tumours.
Certain studies have reported conflicting results between individual plasma concentration …

In order to observe the biodistribution of 5-fluorouracil (5-FU) and its main metabolites in
different kinds of tissue (tumor, liver, kidney, spleen, mucosa, lungs, heart, peritoneum …

A sensitive, reproducible, selective and accurate high performance liquid chromatographic
(HPLC) method for the quantitative determination of 5-flurorouracil in plasma has been …

A HPLC assay method was modified and validated for the determination of 5-fluorouracil in
human red blood cells, plasma and whole blood with a two-fold increased sensitivity …

5-Flourouracil (5-FU) a pyrimidine analogue is widely used in various malignancies
particularly in solid tumors including head and neck, colorectal, and breast cancers …

This paper describes a relatively simple and sensitive high-performance liquid
chromatographic assay (HPLC) with ultraviolet absorbance detection for 5-fluorouracil (5 …

The FU stock solution was diluted 1: lO with water to yield the FU standard solution
containing 10 pg/ml. The CU stock solution was diluted with water to yield the internal …

We report a quantitative assay of 5-fluorouracil (FU) and its metabolite, 5-fluorodihydrouracil
(FDHU) in human urine by used a column-switching high-performance liquid …