Rationale: Vascular endothelial growth factor (VEGF)-B selectively binds VEGF receptor
(VEGFR)-1, a receptor that does not mediate angiogenesis, and is emerging as a major …

The discovery of vascular endothelial growth factors (VEGFs) and their receptors has
considerably improved the understanding of the development and function of endothelial …

Therapeutic angiogenesis improves tissue ischemia by supplementing and supporting the
intrinsic process of angiogenesis. Besides direct administration of angiogenic growth factor …

Since the discovery of the Vascular Endothelial Growth Factor (VEGF) and its leading role in
the angiogenic process, this has been seen as a promising molecule for promoting …

Background—Diabetic cardiomyopathy (DCM) is characterized by microvascular pathology
and interstitial fibrosis, which leads to progressive heart failure; however, the pathogenesis …

Vascular endothelial growth factor (VEGF) is the angiogenic factor promoting and
orchestrating most, if not all, processes of neovascularization taking place in the embryo and …

Vascular endothelial growth factor-B (VEGF-B), discovered over 15 years ago, has long
been seen as one of the more ambiguous members of the VEGF family. VEGF-B is produced …

The vascular endothelial growth factor (VEGF), a homodimeric vasoactive glycoprotein, is
the key mediator of angiogenesis. Angiogenesis, the formation of new blood vessels, is …

Therapeutic angiogenesis is a novel approach to the treatment of coronary and peripheral
vascular disease not amenable to standard revascularization techniques. Vascular …

The formation of new blood vessels (angiogenesis) is critical for both embryonic
development and a variety of normal postnatal physiological processes. Various …