[HTML][HTML] Rodent oocytes express an active adenylyl cyclase required for meiotic arrest

K Horner, G Livera, M Hinckley, K Trinh, D Storm… - Developmental …, 2003 - Elsevier
The intracellular levels of cAMP play a critical role in the meiotic arrest of mammalian
oocytes. However, it is debated whether this second messenger is produced endogenously …

[HTML][HTML] Generation of mouse oocytes defective in cAMP synthesis and degradation: endogenous cyclic AMP is essential for meiotic arrest

S Vaccari, K Horner, LM Mehlmann, M Conti - Developmental biology, 2008 - Elsevier
Although it is established that cAMP accumulation plays a pivotal role in preventing meiotic
resumption in mammalian oocytes, the mechanisms controlling cAMP levels in the female …

Cyclic AMP in oocytes controls meiotic prophase I and primordial folliculogenesis in the perinatal mouse ovary

Y Wang, Z Teng, G Li, X Mu, Z Wang, L Feng… - …, 2015 - journals.biologists.com
In mammalian ovaries, a fixed population of primordial follicles forms during the perinatal
stage and the oocytes contained within are arrested at the dictyate stage of meiotic …

A potential role for AMP-activated protein kinase in meiotic induction in mouse oocytes

SM Downs, ER Hudson, DG Hardie - Developmental biology, 2002 - Elsevier
Cyclic adenosine monophosphate (cAMP) has been implicated as an important regulator of
meiotic maturation in mammalian oocytes. A decrease in cAMP, brought about by the action …

Maintenance of meiotic arrest by increasing [cAMP] i may have physiological relevance in bovine oocytes

H Aktas, MB Wheeler, NL First… - …, 1995 - rep.bioscientifica.com
Invasive adenylate cyclase (iAC) reversibly inhibits spontaneous maturation of cumulus-
enclosed bovine oocytes by increasing the intracellular concentration of cAMP,[cAMP] i. In …

[HTML][HTML] Maintenance of meiotic prophase arrest in vertebrate oocytes by a Gs protein-mediated pathway

RR Kalinowski, CH Berlot, TLZ Jones, LF Ross… - Developmental …, 2004 - Elsevier
Maintenance of meiotic prophase arrest in fully grown vertebrate oocytes depends on an
elevated level of cAMP in the oocyte. To investigate how the cAMP level is regulated, we …

Regulation of meiotic maturation

FJ Richard - Journal of animal science, 2007 - academic.oup.com
Mammalian oocytes are arrested at prophase of the first meiotic division before induction of
maturation by the preovulatory LH surge. In vitro, oocyte maturation occurs spontaneously …

[HTML][HTML] Role of cyclic nucleotide phosphodiesterases in resumption of meiosis

M Conti, CB Andersen, FJ Richard… - Molecular and cellular …, 1998 - Elsevier
In the follicles of the mammalian and amphibian ovary, oocyte maturation is arrested at the
prophase of the first meiotic division. Prior to ovulation, oocytes reenter the cell cycle …

Follicle-stimulating hormone induces a gap junction-dependent dynamic change in [cAMP] and protein kinase a in mammalian oocytes

RJ Webb, F Marshall, K Swann, J Carroll - Developmental biology, 2002 - Elsevier
The second messenger cyclic adenosine 5′ monophosphate (cAMP) has been implicated
in controlling meiotic maturation. To date, there have been no direct measurements of cAMP …

Roles of cAMP in regulation of both MAP kinase and p34cdc2 kinase activity during meiotic progression, especially beyond the MI stage

M Shimada, T Terada - Molecular Reproduction and …, 2002 - Wiley Online Library
Time‐dependent changes in the level of adenosine cyclic AMP (cAMP) in porcine oocytes
during meiotic progression from the germinal vesicle stage (GV stage) to the metaphase II …