The pyramidal neuron loss in dorsal rat hippocampus was determined 4 days after ip
administration of 10 or 20 mg/kg kainic acid (KA). Histological examination revealed that …

Stereotaxic injection of nmol quantities of kainic acid (KA) into the rat hippocampus induced
selective degeneration of nerve cell bodies in this brain region. Vulnerability to the …

Male, Fischer-344 rats were pretreated with MK-801 (0.1, 1.0 or 10.0 mg/kg, ip) prior to
bilateral injection of kainate (0.33 μg/site) into the dorsal and ventral hippocampus. Kainate …

Intraventricular injection of kainic acid produced a characteristic necrosis in the hippocampal
CA3 region of adult rabbits. Neurons in immature rabbit hippocampus were relatively …

Neurons of dorsal root ganglia and of superior cervical ganglia did not display any
morphological signs of degeneration when kainic acid (KA) was administered either …

Transection of the non-glutamatergic septohippocampal fibers 3–5 days prior to
intrahippocampal microinjection of 1 μg kainic acid (KA) or 3 μg ibotenic acid (IBO) protect …

The present study used Nissl stains and glutamate decarboxylase immunoreactivity (GAD-
IR) to quantify the acute and chronic toxicity of kainic acid (KA) on focal and remote …

Kainic acid (KA), a potent neuroexcitatory and neurotoxic analog of glutamate (Glu), induces
a widespread pattern of brain damage when administered subcutaneously to adult rats. The …

The septal nuclei are major target areas for fibers arising in the hippocampal formation,
some originating in the CA3 pyramidal cells in the hippocampus proper 26. These CA3 cells …

The effect of iontophoretically applied kainic acid on the response of CA1 neurones to
Schaffer collateral stimulation has been studied in rat hippocampal slices. Brief applications …