The endothelium controls vascular tone not only by releasing nitric oxide (NO) and
prostacyclin but also by other pathways causing hyperpolarization of the underlying smooth …

Institut de Recherches Internationale Servier, 6 Place des Pleides, 92415 Courbevoie,
Cedex, FranceINTRODUCTIONEndothelial cells synthesise and release vasoactive …

The endothelium maintains vascular homeostasis through the release of active vasodilators.
Although nitric oxide (NO) is recognized as the primary factor at level of conduit arteries …

An endothelium‐derived hyperpolarizing factor (EDHF) that is distinct from nitric oxide (NO)
and prostanoids has been widely hypothesized to hyperpolarize and relax vascular smooth …

Endothelial cells control the tone and the growth of the underlying vascular smooth muscle
by releasing Nitric Oxide (NO). This introduction summarizes the early experiments which …

The chemical identification and functional characterization of endothelium-derived
hyperpolarizing factors varies depending on vascular size, vascular bed and species. Three …

Endothelium plays a crucial role in the regulation of cardiovascular homeostasis through the
release of vasoactive factors. Besides nitric oxide (NO) and prostacyclin, increasing …

Background—Left internal mammary arteries (LIMAs) synthesize endothelium-derived
hyperpolarizing factor (EDHF), a short-lived K+ channel activator that persists after inhibition …

The endothelial cells inhibit the tone of the underlying vascular smooth muscle by releasing
endothelium-derived relaxing factors (EDRF). The existence of at least two such factors …

Endothelial function refers to a multitude of physiological processes that maintain healthy
homeostasis of the vascular wall. Exposure of the endothelium to cardiac risk factors results …