Appendicitis is the most common abdominal surgical emergency, but its aetiology is not fully
understood. We and others have proposed that allergic responses play significant roles in its …

In the last decade, new information was achieved on mast cells (MC). Their origin is
assumed to be different from that of the basophils. There are two types of MC with …

Objective.—The pathogenesis of appendicitis remains poorly understood. However, there is
increasing evidence of involvement of the enteric nervous system in immune regulation and …

The staining properties of tissue mast cells are influenced by the method of fixation.
Differences in fixation and staining techniques may explain the contradictory results in the …

Mast cells are versatile tissue regulator cells controlling major intestinal functions such as
epithelial secretion, epithelial permeability, blood flow, neuroimmune interactions, and …

Background: Mast cells have been studied for decades due to their prominent role in normal
homeostasis and various pathologies. They display a diversity of roles and are proposed to …

The mast cell contains a variety of chemical mediators which are thought to participate in the
inflammatory response. The position of this cell at the mucosal and cutaneous surfaces and …

In patients with mastocytosis, gastrointestinal symptoms are a frequent phenomenon.
However, there are only limited data about the quantity and distribution pattern of mast cells …

Objective: The role of mast cells as the key effector of allergic inflammation, anaphylactic
inflammatory reactions and in the pathogenesis of chronic inflammation, is well-known. The …

An avidin–biotin enhanced immunoperoxidase procedure using monoclonal antibodies
(AA1, AA3, and AA5) prepared against human mast cell tryptase resulted in intense staining …