Fluorescence-guided surgery: a review on timing and use in brain tumor surgery

AJ Schupper, M Rao, N Mohammadi, R Baron… - Frontiers in …, 2021 - frontiersin.org
Fluorescence-guided surgery (FGS) allows surgeons to have improved visualization of
tumor tissue in the operating room, enabling maximal safe resection of malignant brain …

Indocyanine-green for fluorescence-guided surgery of brain tumors: evidence, techniques, and practical experience

SS Cho, R Salinas, JYK Lee - Frontiers in surgery, 2019 - frontiersin.org
The primary treatment for brain tumors often involves surgical resection for diagnosis, relief
of mass effect, and prolonged survival. In neurosurgery, it is of utmost importance to achieve …

Agents for fluorescence-guided glioma surgery: a systematic review of preclinical and clinical results

JT Senders, IS Muskens, R Schnoor, AV Karhade… - Acta …, 2017 - Springer
Background Fluorescence-guided surgery (FGS) is a technique used to enhance
visualization of tumor margins in order to increase the extent of tumor resection in glioma …

Intraoperative fluorescence-guided resection of high-grade gliomas: a comparison of the present techniques and evolution of future strategies

Y Li, R Rey-Dios, DW Roberts, PA Valdés… - World neurosurgery, 2014 - Elsevier
Objective Fluorescence guidance has a demonstrated potential in maximizing the extent of
high-grade glioma resection. Different fluorophores (fluorescent biomarkers), including 5 …

Intraoperative fluorescence imaging for personalized brain tumor resection: current state and future directions

E Belykh, NL Martirosyan, K Yagmurlu, EJ Miller… - Frontiers in …, 2016 - frontiersin.org
Introduction Fluorescence-guided surgery is one of the rapidly emerging methods of surgical
“theranostics.” In this review, we summarize current fluorescence techniques used in …

Fluorescence-guided surgery in the surgical treatment of gliomas: Past, present and future

R Sun, H Cuthbert, C Watts - Cancers, 2021 - mdpi.com
Simple Summary Gliomas are aggressive central nervous system tumours. The emergence
and recent widespread adoption of 5-aminolevulinic acid and fluorescence guided surgery …

Turning on the light for brain tumor surgery: a 5-aminolevulinic acid story

DJ McCracken, AJ Schupper, N Lakomkin… - Neuro …, 2022 - academic.oup.com
To aid surgeons in more complete and safe resection of brain tumors, adjuvant technologies
have been developed to improve visualization of target tissue. Fluorescence-guided surgery …

Optical principles of fluorescence-guided brain tumor surgery: a practical primer for the neurosurgeon

DY Zhang, S Singhal, JYK Lee - Neurosurgery, 2019 - journals.lww.com
Fluorescence-guided surgery is a rapidly growing field that has produced some of the most
important innovations in surgical oncology in the past decade. These intraoperative imaging …

Fluorescence-guided surgery for high-grade gliomas: state of the art and new perspectives

G Palmieri, F Cofano, LF Salvati… - … in cancer research …, 2021 - journals.sagepub.com
High-grade gliomas are aggressive tumors that require multimodal management and gross
total resection is considered to be the first crucial step of treatment. Because of their …

Fluorescent-guided surgical resection of glioma with targeted molecular imaging agents: a literature review

SEL Craig, J Wright, AE Sloan, SM Brady-Kalnay - World neurosurgery, 2016 - Elsevier
The median life expectancy after a diagnosis of glioblastoma is 15 months. Although
chemotherapeutics may someday cure glioblastoma by killing the highly dispersive …