Microglia: housekeeper of the central nervous system

JA Kabba, Y Xu, H Christian, W Ruan, K Chenai… - Cellular and molecular …, 2018 - Springer
Microglia, of myeloid origin, play fundamental roles in the control of immune responses and
the maintenance of central nervous system homeostasis. These cells, just like peripheral …

Role of microglia in neurological disorders and their potentials as a therapeutic target

L Du, Y Zhang, Y Chen, J Zhu, Y Yang… - Molecular neurobiology, 2017 - Springer
Microglia are resident macrophage-like immune cells in the central nervous system (CNS)
and play a vital role in both physiological and pathological conditions, including restoring …

Microglia function in the central nervous system during health and neurodegeneration

M Colonna, O Butovsky - Annual review of immunology, 2017 - annualreviews.org
Microglia are resident cells of the brain that regulate brain development, maintenance of
neuronal networks, and injury repair. Microglia serve as brain macrophages but are distinct …

Microglial cell origin and phenotypes in health and disease

K Saijo, CK Glass - Nature Reviews Immunology, 2011 - nature.com
Microglia—resident myeloid-lineage cells in the brain and the spinal cord parenchyma—
function in the maintenance of normal tissue homeostasis. Microglia also act as sentinels of …

Microglia: phagocyte and glia cell

F Vilhardt - The international journal of biochemistry & cell biology, 2005 - Elsevier
Microglia are the resident immune cells of the brain, and are located within the brain
parenchyme behind the blood–brain barrier. They originate from mesodermal hemapoietic …

Microglia in neurological diseases: a road map to brain-disease dependent-inflammatory response

S Bachiller, I Jiménez-Ferrer, A Paulus… - Frontiers in cellular …, 2018 - frontiersin.org
Microglia represent a specialized population of macrophages-like cells in the central
nervous system (CNS) considered immune sentinels that are capable of orchestrating a …

Microglia phenotype diversity

M Olah, K Biber, J Vinet… - CNS & Neurological …, 2011 - ingentaconnect.com
Microglia, the tissue macrophages of the brain, have under healthy conditions a resting
phenotype that is characterized by a ramified morphology. With their fine processes …

Microglia in neuroinflammation and neurodegeneration: from understanding to therapy

L Muzio, A Viotti, G Martino - Frontiers in neuroscience, 2021 - frontiersin.org
Microglia are the resident macrophages of the central nervous system (CNS) acting as the
first line of defense in the brain by phagocytosing harmful pathogens and cellular debris …

Role of microglia in neuronal degeneration and regeneration

L Walter, H Neumann - Seminars in immunopathology, 2009 - Springer
Microglial cells, the resident macrophage population of the central nervous system (CNS),
actively scan tissue under both normal and pathologic contexts. Their resulting engagement …

Microglia plasticity during health and disease: an immunological perspective

A Shemer, D Erny, S Jung, M Prinz - Trends in immunology, 2015 - cell.com
Microglia are macrophages of the central nervous system (CNS) that continuously scrutinize
their environment for damage. They colonize the cephalic mesenchyme during …