The rapidly growing collection of diverse genome-scale data from multiple tumor types
sheds light on various aspects of the underlying tumor biology. With the objective to identify …

Recent work using expression profiling to computationally predict the estrogen receptor (ER)
status of breast tumors has revealed that certain tumors are characterized by a high …

Background Accurate classification of breast cancer molecular subtypes is crucial in
determining treatment strategies and predicting clinical outcomes. This classification largely …

We studied androgen receptor (AR) gene expression in primary breast cancer (BC) to
determine associations with clinical characteristics and outcomes in the I-SPY 1 study. AR …

Substantial controversy exists about the prognostic role of tumor subtypes in male breast
cancer (MaBC). The aim of this study was to analyze the characteristics of each tumor …

Purpose Limited data exist on the molecular biology, treatment, and outcomes of breast
cancer in men, and much of our understanding in this area remains largely an extrapolation …

Simple Summary Breast cancer (BC) is the second largest cause of death for cancer in
women worldwide. Different studies have shown that the androgen receptor (AR), a …

Biomarkers can be used for diagnosis, prognosis, and prediction in targeted therapy. The
estrogen receptor α (ERα) and human epidermal growth factor receptor 2 (HER2) are …

Introduction When making treatment decisions, oncologists often stratify breast cancer (BC)
into a low-risk group (low-grade estrogen receptor-positive (ER+)), an intermediate-risk …

Background Male breast cancer (BC) is rare, managed by extrapolation from female BC. The
International Male BC Program aims to better characterize and manage this disease. We …