New therapies in development for the management of non‐infectious uveitis: a review
Uveitis is a spectrum of inflammatory disorders characterized by ocular inflammation and is
one of the leading causes of preventable visual loss. The main aim of the treatment of uveitis …
one of the leading causes of preventable visual loss. The main aim of the treatment of uveitis …
Immune mechanisms in uveitis
L Chen, LK Gordon - Uveitis and Immunological Disorders, 2005 - Springer
∑ The eye is a site of immune privilege that results from local structural features, local
expression of soluble immunosuppressive agents, and cell surface expression of negative …
expression of soluble immunosuppressive agents, and cell surface expression of negative …
Mouse models of autoimmune uveitis
IP Klaska, JV Forrester - Current pharmaceutical design, 2015 - ingentaconnect.com
Uveitis is a sight threatening intraocular inflammation accounting for approximately 10% of
blindness worldwide. On the basis of aetiology, disease can be classified as infectious or …
blindness worldwide. On the basis of aetiology, disease can be classified as infectious or …
Editorial (Thematic Issue: Uveitis: Pathology, Molecular Mechanisms and Therapy)
P Yang - Current Molecular Medicine, 2015 - ingentaconnect.com
investigations of uveitis in the aspects of animal model and patients and offers new insights
in the pathogenesis and treatment of uveitis.“Spontaneous ocular autoimmunity in mice …
in the pathogenesis and treatment of uveitis.“Spontaneous ocular autoimmunity in mice …
Therapies in development for non-infectious uveitis
Uveitis represents a spectrum of diseases characterized by ocular inflammation that leads to
significant visual loss if left untreated. Adequate, long-term control of inflammation with …
significant visual loss if left untreated. Adequate, long-term control of inflammation with …
[HTML][HTML] Autoimmune and autoinflammatory mechanisms in uveitis
The eye, as currently viewed, is neither immunologically ignorant nor sequestered from the
systemic environment. The eye utilises distinct immunoregulatory mechanisms to preserve …
systemic environment. The eye utilises distinct immunoregulatory mechanisms to preserve …
[HTML][HTML] Current concepts and future directions in the pathogenesis and treatment of non-infectious intraocular inflammation
The blockbuster drug paradigm is under increasing scrutiny across the biopharmaceutical
industry. Intraocular inflammation poses particular challenges to this, given the …
industry. Intraocular inflammation poses particular challenges to this, given the …
Biological response modifiers in the treatment of noninfectious uveitis
LJ Kopplin, AS Shifera, EB Suhler… - International …, 2015 - journals.lww.com
Uveitis comprises a heterogenous group of diseases with different inflammatory pathways
and immune phenotypes responsible for various uveitic entities. 1 Its pathogenesis is …
and immune phenotypes responsible for various uveitic entities. 1 Its pathogenesis is …
Clinical and functional evaluation of ocular inflammatory disease using the model of experimental autoimmune uveitis
J Chen, RR Caspi - Immunological Tolerance: Methods and Protocols, 2019 - Springer
Non-infections uveitis in humans is an autoimmune disease of the retina and uvea that can
be blinding if untreated. Its laboratory equivalent is experimental autoimmune uveitis (EAU) …
be blinding if untreated. Its laboratory equivalent is experimental autoimmune uveitis (EAU) …
[HTML][HTML] Autoimmune uveitis: the associated proinflammatory molecules and the search for immunoregulation
Uveitis is an intraocular inflammatory disease causing a significant visual impairment. The
disease can be idiopathic, associated with infectious and systemic disorders or arisen from …
disease can be idiopathic, associated with infectious and systemic disorders or arisen from …