Autoimmune uveitis (AU), an inflammatory non-infectious process of the vascular layer of the
eye, can lead to visual impairment and, in the absence of a timely diagnosis and suitable …

purpose. To determine the association between 17 single nucleotide polymorphisms (SNPs)
of tumor necrosis factor-α, lymphotoxin-α, and the TNF-receptors genes (TNF, LTA, and …

Methods EAU was induced in C57BL/6 mice by subcutaneous application of IRBP
(interphotoreceptor retinoid binding protein) in complete Freunds adjuvant and …

Although traditionally the adaptive immune system has been viewed as the essential
contributor to autoimmune diseases, the evidence implicating the innate immune system has …

Uveitis is an autoimmune disease that usually damages the vision function, leading to poor
visual quality in patients. As an autoimmune ocular inflammatory disease, the pathogenesis …

Uveitis, or intraocular inflammatory disease, is an old term that has been qualified with
additional terms such as iritis, cyclitis, and iridocyclitis since the beginning of the last century …

Over the past several decades, animal models of autoimmune uveitis directed at eye-
specific antigens (Ags) have been developed. These have allowed researchers to …

Uveitis is a significant cause of ocular morbidity and accounts for approximately 5–10% of
visual impairments worldwide, particularly among the working-age population. Infections are …

Non-infectious uveitis comprehends a heterogeneous group of intraocular inflammatory
diseases that arise without a known infectious trigger. This complex group of disorders is …

Purpose Early identification of patients with noninfectious uveitis requiring steroid-sparing
immunomodulatory therapy (IMT) is currently lacking in objective molecular biomarkers. We …