Emerging reports reveal that activating Toll-like receptor-2 (TLR2)–MyD88 signals in CD8 T
lymphocytes enhances cytokine production and cytotoxicity; however, the signaling pathway …

Toll-like receptor 2 (TLR2) serves as a co-stimulatory receptor for human T cells by
enhancing T cell receptor (TCR)-induced cytokine production and proliferation. However, it …

Toll‐like receptors (TLR) have been indicated as germline‐encoded receptors for sensing a
variety of pathogens. Although the role of TLR in innate immunity is beyond question, their …

While Toll-like receptors (TLRs) represent one of the best characterized innate immune
pathways, evidence suggests that TLRs are not restricted to innate leukocytes and some …

CD4+ T cells recognize antigens through their T cell receptors (TCRs); however, additional
signals involving costimulatory receptors, for example, CD28, are required for proper T cell …

We have recently demonstrated that mycobacterial ligands engage Toll like receptor 2
(TLR2) on CD4+ T cells and up‐regulate T‐cell receptor (TCR) triggered Th1 responses in …

Toll-like receptor (TLR) signaling activation by pathogens is critical to the induction of
immune responses, and demands tight regulation. We describe in this study that CC …

Toll-like receptors (TLRs) are able to interact with pathogen-derived products and their
signals induce the coordinated activation of innate and adaptive immune mechanisms …

Toll-like receptors (TLRs) are among the fundamental molecules that alert the immune
system to the presence of an infection by recognizing pathogen-associated molecules. Much …

γδ T cells express several different toll-like receptor (TLR) s. The role of MyD88-dependent
TLR signaling in TCR activation of murine γδ T cells is incompletely defined. Here, we report …