Neural tube defects: a review of human and animal studies on the etiology of neural tube defects

LR Campbell, DH Dayton, GS Sohal - Teratology, 1986 - Wiley Online Library
Although neural tube defects are a common congenital anomaly, their etiology is not known.
Human studies have emphasized the pathology and epidemiology of the defects and …

Investigations into the etiology of neural tube defects

RM Cabrera, DS Hill, AJ Etheredge… - Birth Defects Research …, 2004 - Wiley Online Library
Neural tube defects (NTDs) are serious malformations affecting approximately 1 per 1000
births, yet the mechanisms by which they arise are unknown. There have been consistent …

Apparent lability of neural tube closure in laboratory animals and humans

JM DeSesso, AR Scialli… - American journal of …, 1999 - Wiley Online Library
Neural tube defects (NTDs), a set of structural abnormalities affecting the brain, spinal cord,
and the skeletal and connective tissues that protect them, are common malformations …

Etiologic heterogeneity of neural tube defects: clues from epidemiology

MJ KHOURY, JD ERICKSON… - American Journal of …, 1982 - academic.oup.com
The epidemiology of neural tube defects was reviewed, using data from two birth defects
surveiliance systems: the nationwide Birth Defects Monitoring Program and the Metropolitan …

Studies in neural tube defects I. Epidemiologic and etiologic aspects

NC Myrianthopoulos, M Melnick… - American journal of …, 1987 - Wiley Online Library
Abstract In the NIH Collaborative Perinatal Project, a prospective study of over 53,000
pregnant women and their offspring, 71 single‐born children (13.33/10,000) were found to …

The embryonic development of mammalian neural tube defects

AJ Copp, FA Brook, JP Estibeiro, ASW Shum… - Progress in …, 1990 - Elsevier
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Clues to the aetiology of neural tube malformations

CO Carter - Developmental Medicine & Child Neurology, 1974 - Wiley Online Library
The aetiology of neural tube malformations may include both genetic and environmental
elements. The genetic factors considered are:(a) a preponderance of one or other sex;(b) …

An epidemiologic study of neural tube defects in Los Angeles County II. Etiologic factors in an area with low prevalence at birth

LE Sever - Teratology, 1982 - Wiley Online Library
Epidemiologic characteristics of neural tube defect (NTD) births occurring in Los Angeles
County, California, residents during the period 1966–1972 are presented. The prevalence at …

[引用][C] Causation of neural tube defects: clues from epidemiology

IAN Leck - British Medical Bulletin, 1974 - academic.oup.com
The most dramatic of all errors of nervous system development are those that arise in the
embryo when the closure of the neural tube and its submergence within the mesoderm are …

Human neural tube defects: developmental biology, epidemiology, and genetics

ER Detrait, TM George, HC Etchevers, JR Gilbert… - Neurotoxicology and …, 2005 - Elsevier
Birth defects (congenital anomalies) are the leading cause of death in babies under 1 year
of age. Neural tube defects (NTD), with a birth incidence of approximately 1/1000 in …