Abstract Amyotrophic Lateral Sclerosis (ALS) is a fatal, rapidly progressive,
neurodegenerative disease caused by motor neuron degeneration. Despite extensive …

Astrocytes are key players in the progression of amyotrophic lateral sclerosis (ALS).
Previously, gene expression profiling of astrocytes from the pre-symptomatic stage of the …

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disorder,
characterized by the degeneration of upper and lower motor neurons of the motor cortex …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease, involving the selective
degeneration of cortical upper synapses in the primary motor cortex (M1). Excitotoxicity in …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by
motor neuron (MN) loss. Recent evidences highlight astrocytes as important players in MN …

Astrocytes emerge as key players in motor neuron degeneration in Amyotrophic Lateral
Sclerosis (ALS). Whether astrocytes cause direct damage by releasing toxic factors or …

Amyotrophic lateral sclerosis (ALS) is a fatal, adult-onset neurodegenerative disease that is
characterized by the death of upper and lower motor neurons. Recent studies have made it …

Glutamate‐induced excitotoxicity is suggested to play a central role in the development of
amyotrophic lateral sclerosis (ALS), although it is still unclear whether it represents a primary …

Impaired glutamate uptake function of astrocytes associated with accumulation of
extracellular glutamate is a well-documented feature of amyotrophic lateral sclerosis (ALS) …

Non-cell autonomous mechanisms are involved in the pathogenesis of amyotrophic lateral
sclerosis (ALS), an adult neurodegenerative disease characterized by selective motor …