Intramuscular lipid metabolism, insulin action, and obesity
LA Consitt, JA Bell, JA Houmard - IUBMB life, 2009 - Wiley Online Library
With the increasing prevalence of obesity, research has focused on the molecular
mechanism (s) linking obesity and skeletal muscle insulin resistance. Metabolic alterations …
mechanism (s) linking obesity and skeletal muscle insulin resistance. Metabolic alterations …
The molecular mechanism linking muscle fat accumulation to insulin resistance
MW Hulver, GL Dohm - Proceedings of the Nutrition Society, 2004 - cambridge.org
Skeletal muscle insulin resistance is a co-morbidity of obesity and a risk factor for the
development of type 2 diabetes mellitus. Insulin resistance is associated with the …
development of type 2 diabetes mellitus. Insulin resistance is associated with the …
Role of lipid-derived mediators in skeletal muscle insulin resistance
A Taube, K Eckardt, J Eckel - American Journal of …, 2009 - journals.physiology.org
Imbalance between nutritional intake and energy expenditure has been described to
culminate in obesity, which predisposes to insulin resistance and type 2 diabetes mellitus. In …
culminate in obesity, which predisposes to insulin resistance and type 2 diabetes mellitus. In …
Muscular diacylglycerol metabolism and insulin resistance
S Timmers, P Schrauwen, J de Vogel - Physiology & behavior, 2008 - Elsevier
Failure of insulin to elicit an increase in glucose uptake and metabolism in target tissues
such as skeletal muscle is a major characteristic of non-insulin dependent type 2 diabetes …
such as skeletal muscle is a major characteristic of non-insulin dependent type 2 diabetes …
Skeletal muscle triglyceride: marker or mediator of obesity-induced insulin resistance in type 2 diabetes mellitus?
BH Goodpaster, DE Kelley - Current diabetes reports, 2002 - Springer
The inability of insulin to stimulate glucose metabolism in skeletal muscle is a classic
characteristic of type 2 diabetes, but this insulin resistance entails altered patterns of lipid …
characteristic of type 2 diabetes, but this insulin resistance entails altered patterns of lipid …
[PDF][PDF] Weight loss and exercise: implications for muscle lipid metabolism and insulin action
JR Berggren, MW Hulver, GL Dohm… - Medicine & Science in …, 2004 - paulogentil.com
ABSTRACT BERGGREN, JR, MW HULVER, GL DOHM, and JA HOUMARD. Weight Loss
and Exercise: Implications for Muscle Lipid Metabolism and Insulin Action. Med. Sci. Sports …
and Exercise: Implications for Muscle Lipid Metabolism and Insulin Action. Med. Sci. Sports …
The role of intramuscular lipid in insulin resistance
BD Hegarty, SM Furler, J Ye, GJ Cooney… - Acta Physiologica …, 2003 - Wiley Online Library
There is interest in how altered lipid metabolism could contribute to muscle insulin
resistance. Many animal and human states of insulin resistance have increased muscle …
resistance. Many animal and human states of insulin resistance have increased muscle …
Role of skeletal muscle lipids in the pathogenesis of insulin resistance of obesity and type 2 diabetes
M Gilbert - Journal of diabetes investigation, 2021 - Wiley Online Library
Obesity predisposes individuals to the development of insulin resistance, which is a risk
factor for type 2 diabetes, and muscle plays a central role in this phenomenon. Insulin …
factor for type 2 diabetes, and muscle plays a central role in this phenomenon. Insulin …
Obesity-associated insulin resistance in skeletal muscle: role of lipid accumulation and physical inactivity
K Eckardt, A Taube, J Eckel - Reviews in Endocrine and Metabolic …, 2011 - Springer
An alarming increase in the prevalence of obesity, type 2 diabetes mellitus, and associated
diseases can be observed world-wide during the past 20 years. In obesity, profound …
diseases can be observed world-wide during the past 20 years. In obesity, profound …
High-fat load: mechanism (s) of insulin resistance in skeletal muscle
Skeletal muscle from sedentary obese patients is characterized by depressed electron
transport activity, reduced expression of genes required for oxidative metabolism, altered …
transport activity, reduced expression of genes required for oxidative metabolism, altered …