Decreased activation of placental mTOR family members is associated with the induction of intrauterine growth restriction by secondhand smoke in the mouse

C Mejia, J Lewis, C Jordan, J Mejia, C Ogden… - Cell and Tissue …, 2017 - Springer
Cigarette smoke is known to be a risk for the development of intrauterine growth restriction
(IUGR). Our objective was to assess the effects of secondhand smoke (SHS) during …

Disruption of oxygen-regulated responses underlies pathological changes in the placentas of women who smoke or who are passively exposed to smoke during …

O Genbacev, MT McMaster, T Zdravkovic… - Reproductive …, 2003 - Elsevier
Previously, we showed that maternal smoking harms human placental development by
changing the balance between cytotrophoblast (CTB) proliferation and differentiation. To …

Effect of maternal tobacco smoke exposure on the placental transcriptome

H Bruchova, A Vasikova, M Merkerova, A Milcova… - Placenta, 2010 - Elsevier
Smoking in pregnancy increases a woman's risk of preterm delivery resulting in serious
neonatal health problems and chronic lifelong disabilities for the children (eg, mental …

Macaque Trophoblast Migration toward RANTES Is Inhibited by Cigarette Smoke–Conditioned Medium

TL Thirkill, H Vedagiri, GC Douglas - Toxicological Sciences, 2006 - academic.oup.com
Trophoblast migration within the endometrium and uterine vasculature is essential for
normal placental and fetal development. We previously demonstrated that macaque …

Effects of cigarette smoke extracts on cell cycle, cell migration and endocrine activity in human placental cells

CW Kim, HM Lee, K Lee, B Kim, MY Lee… - Reproductive Toxicology, 2017 - Elsevier
Maternal smoking during pregnancy is known to be related to adverse pregnancy results
associated with trophoblast proliferation and cell cycle progression. Moreover, many …

[HTML][HTML] Effects of cigarette smoke on fertilization and embryo development in vivo

J Huang, M Okuka, M McLean, DL Keefe, L Liu - Fertility and sterility, 2009 - Elsevier
OBJECTIVE: To determine the effects of smoking on eggs and subsequent embryo
development by maternal exposure to cigarette smoke. DESIGN: Mice were exposed to …

Hormonal changes accompanying cigarette smoke-induced preterm births in a mouse model

SP Ng, BG Steinetz, SG Lasano… - … Biology and Medicine, 2006 - journals.sagepub.com
Epidemiologic evidence indicates that maternal smoking increases the risk of preterm birth.
While a number of plausible mechanisms for early delivery have been offered, the role of …

The adverse effects of maternal smoking on the human placenta: a review

T Zdravkovic, O Genbacev, MT McMaster, SJ Fisher - Placenta, 2005 - Elsevier
Studies of placental pathologies associated with maternal cigarette smoking have led to
many interesting observations. For example, maternal smoking impairs human placental …

Morphological and biological effects of maternal exposure to tobacco smoke on the feto-placental unit

E Jauniaux, GJ Burton - Early human development, 2007 - Elsevier
Active and passive maternal smoking has a damaging effect in every trimester of human
pregnancy. Cigarette smoke contains scores of toxins which exert a direct effect on the …

[HTML][HTML] The effect of cigarette smoke on fertilization and pre-implantation development: assessment using animal models, clinical data, and stem cells

P Talbot, S Lin - Biological Research, 2011 - SciELO Chile
Numerous studies have repeatedly shown that women who smoke experience problems
establishing and maintaining pregnancies, and recent work has further demonstrated that …