Extremely AT-rich DNA sequences present a challenging template for specific recognition by
RNA polymerase. In bacteria, this is because the promoter− 10 hexamer, the major DNA …

A class of trans-acting mutations, which alter the osmoregulated expression of the
Escherichia coli proU operon, maps at 27 min on the chromosome in a locus we have called …

Prokaryotic genomes are compacted by association with small basic proteins, generating
what has been termed bacterial chromatin. The ubiquitous DNA-binding protein HU serves …

The effect of the bacterial heat-stable nucleoid-structuring (H-NS) protein on gene
expression is overwhelmingly negative and extends throughout the genome, pointing to an …

Abstract Helix–hairpin–helix (HhH) is a widespread motif involved in non-sequence-specific
DNA binding. The majority of HhH motifs function as DNA-binding modules, however, some …

Recently, the solution structure of the hypothetical protein HI1450 from Haemophilus
influenzae was solved as part of a structure‐based effort to understand function. The …

The binding of E. coli histone-like protein HU to curved and uncurved DNA fragments
containing adenine tracts was characterized by relative binding affinity assay, and compared …

Genomic compaction is an essential characteristic of living organisms. Nucleoid-associated
proteins (NAPs) are a group of small proteins that play crucial roles in chromosome …

Heat-stable nucleoid-structuring protein (H-NS) is one of the main nucleoid proteins
expressed in exponentially growing Escherichia coli cells. In addition to a role in nucleoid …

Nucleoid-associated proteins (NAPs) play central roles in bacterial chromosome
organization and DNA processes. The Escherichia coli YejK protein is a highly abundant …