Structural changes in the region directly adjacent to the DNA-binding helix highlight a possible mechanism to explain the observed changes in the sequence-specific …

I Marsden, C Jin, X Liao - Journal of molecular biology, 1998 - Elsevier
The hepatocyte nuclear factor 3 (HNF-3)/fork head (fkh) family contains a large number of
transcription factors and folds into a winged helix motif. Despite having almost invariable …

H-NS in Gram-negative bacteria: a family of multifaceted proteins

C Tendeng, PN Bertin - Trends in microbiology, 2003 - cell.com
DNA-packaging and the control of gene expression constitute a major challenge for bacteria
to survive and adapt to environmental changes. The use of multiple strategies to solve these …

Molecular aspects of the E. coli nucleoid protein, H-NS: a central controller of gene regulatory networks

RM Williams, S Rimsky - FEMS microbiology letters, 1997 - academic.oup.com
The nucleoid-associated protein H-NS has a central role in the structuring and control of the
enteric bacterial chromosome. This protein has been demonstrated to contribute to the …

DNA topology confers sequence specificity to nonspecific architectural proteins

J Wei, L Czapla, MA Grosner… - Proceedings of the …, 2014 - National Acad Sciences
Topological constraints placed on short fragments of DNA change the disorder found in
chain molecules randomly decorated by nonspecific, architectural proteins into tightly …

HU and IHF: similarities and differences. In Escherichia coli, the lack of HU is not compensated for by IHF

F Boubrik, E Bonnefoy, J Rouvière-Yaniv - Research in microbiology, 1991 - Elsevier
HU is one of the most abundant DNA binding proteins in Escherichia coli. Like the histones,
HU is able to condense DNA in vitro and to introduce negative supercoiling in covalently …

The essentiality and involvement of Streptococcus intermedius histone‐like DNA‐binding protein in bacterial viability and normal growth

D Liu, H Yumoto, K Murakami, K Hirota… - Molecular …, 2008 - Wiley Online Library
Streptococcus intermedius histone‐like DNA‐binding protein (Si‐HLP) is a homodimeric
protein and, conserved with Escherichia coli HU, a well‐documented nucleoid‐associated …

Control of transcription by nucleoid proteins

SM McLeod, RC Johnson - Current opinion in microbiology, 2001 - Elsevier
Nucleoid proteins are a group of abundant DNA binding proteins that modulate the structure
of the bacterial chromosome. They have been recruited as specific negative and positive …

Growth phase-dependent expression profiles of three vital H-NS family proteins encoded on the chromosome of Pseudomonas putida KT2440 and on the pCAR1 …

Z Sun, D Vasileva, C Suzuki-Minakuchi, K Okada… - BMC microbiology, 2017 - Springer
Background H-NS family proteins are nucleoid-associated proteins that form oligomers on
DNA and function as global regulators. They are found in both bacterial chromosomes and …

Indirect recognition in sequence-specific DNA binding by Escherichia coli integration host factor: the role of DNA deformation energy

KA Aeling, ML Opel, NR Steffen… - Journal of biological …, 2006 - ASBMB
Integration host factor (IHF) is a bacterial histone-like protein whose primary biological role
is to condense the bacterial nucleoid and to constrain DNA supercoils. It does so by binding …

HU, the major histone‐like protein of E. coli, modulates the binding of IHF to oriC.

E Bonnefoy, J Rouvière‐Yaniv - The EMBO journal, 1992 - embopress.org
HU is one of the most abundant DNA binding proteins of bacteria. Unlike IHF, integration
host factor of Escherichia coli, with which HU shares many properties, including a strong …