The nuclear factor-κB (NF-κB) signaling pathway regulates multiple processes in innate and
adaptive immune cells. This pathway is involved in inflammation through the regulation of …

The transcription factor NF-κB has been well recognized as a pivotal regulator of
inflammation in rheumatoid arthritis (RA), but recent developments revealed a broad …

NF-κB is an inducible transcription factor that is controlled by the signal activation cascades.
NF-κB controls a number of genes involved in immuno-inflammatory responses, cell cycle …

NF‐κB (nuclear factor kappa light chain enhancer of activated B cells) signaling pathway is
involved in the occurrence and development of various kinds of inflammation, including …

The nuclear factor-κB (NF-κB) family of transcription factors is essential for the expression of
pro-inflammatory cytokines, but can also induce regulatory pathways. NF-κB can be …

Abstract Interleukin (IL)‑1β serves a crucial role in the progression of rheumatoid arthritis.
Previous studies have indicated that the ERK/STAT1 signaling pathway may be involved in …

Background: Rheumatoid arthritis (RA) is the most common inflammatory arthritis and is a
major cause of disability. The nuclear factor-kappa-light-chain-enhancer of activated B cells …

Osteoarthritis (OA) is a type of joint disease associated with wear and tear, inflammation,
and aging. Mechanical stress along with synovial inflammation promotes the degradation of …

The transcription factor NF-κB plays crucial roles in the regulation of inflammation and
mmune responses, and inappropriate NF-κB activity has been linked with many autoimmune …

In the synovial cells of patients with RA, activation of the nuclear factor-κB (NF-κB) pathway
results in the transactivation of a multitude of responsive genes that contribute to the …