Clinical pharmacology of corticosteroids

DM Williams - Respiratory care, 2018 - rc.rcjournal.com
Corticosteroids have numerous applications in treating inflammation and diseases of
immune function based on their significant anti-inflammatory and immunosuppressive …

Current issues for establishing inhaled corticosteroids as the antiinflammatory agents of choice in asthma

PJ Barnes - Journal of allergy and clinical immunology, 1998 - Elsevier
Airway inflammation appears to be present even in the mildest of asthma, and inhaled
corticosteroids now form the mainstay of asthma therapy. Inhaled corticosteroids largely …

Inhaled corticosteroids: past lessons and future issues

DB Allen, L Bielory, H Derendorf, R Dluhy… - Journal of Allergy and …, 2003 - Elsevier
Inhaled corticosteroids play a pivotal role in the treatment of asthma. Inhalation permits
effective delivery of the corticosteroid in high concentration to target sites within the lung …

Efficacy of inhaled corticosteroids in asthma

PJ Barnes - Journal of allergy and clinical immunology, 1998 - Elsevier
Inhaled corticosteroids have now become established as first-line therapy for patients with
persistent asthma. Corticosteroids are the only currently available asthma therapy that …

Efficacy and safety of inhaled corticosteroids: new developments

PJ Barnes, S Pedersen, WW Busse - American journal of respiratory …, 1998 - atsjournals.org
Inhaled corticosteroids have revolutionized the treatment of asthma and have now become
the mainstay of therapy for patients with chronic disease (1). In a supplement to this journal …

Inhaled corticosteroids: potency, dose equivalence and therapeutic index

PT Daley‐Yates - British journal of clinical pharmacology, 2015 - Wiley Online Library
Glucocorticosteroids are a group of structurally related molecules that includes natural
hormones and synthetic drugs with a wide range of anti‐inflammatory potencies. For …

[HTML][HTML] Suppl 1: M2: systemic effects of inhaled corticosteroids: an overview

D Pandya, A Puttanna, V Balagopal - The open respiratory …, 2014 - ncbi.nlm.nih.gov
Inhaled corticosteroids (ICS) are common medications, used in respiratory medicine for
controlling conditions such as asthma and other obstructive airway diseases. The systemic …

Establishing a therapeutic index for the inhaled corticosteroids: part I: pharmacokinetic/pharmacodynamic comparison of the inhaled corticosteroids

HW Kelly - Journal of allergy and clinical immunology, 1998 - Elsevier
The inhaled corticosteroids contain physicochemical differences that alter both
glucocorticoid receptor-binding characteristics and the pharmacokinetic variables of these …

Comparison of inhaled corticosteroids: an update

HW Kelly - Annals of Pharmacotherapy, 2009 - journals.sagepub.com
Objective: To review the basis for the estimated comparative daily dosages of inhaled
corticosteroids for children and adults that are presented in the National Heart, Lung, and …

Inhaled corticosteroids in COPD: a controversy

PJ Barnes - Respiration, 2010 - karger.com
Inhaled corticosteroids (ICS) are now very widely used in high doses in the management of
COPD patients. In sharp contrast to the situation in asthma, ICS provide little or no benefit in …