Abstract Background Bile acids (BAs) are synthesized by the liver and modified by gut
bacteria, and may play an intermediary role between the gut microbiome and liver in …

Background & Aims Non-alcoholic fatty liver disease (NAFLD) is characterized by dysbiosis.
The bidirectional effects between intestinal microbiota (IM) and bile acids (BA) suggest that …

Background Dysregulated bile acid (BA) metabolism has been linked to steatosis,
inflammation, and fibrosis in nonalcoholic fatty liver disease (NAFLD). Aim To determine …

Objective Metabolomic studies suggest plasma levels of bile acids (BAs) are elevated
amongst subjects with non-alcoholic fatty liver disease (NAFLD) compared to healthy …

Abstract Background and Aims Bile acid (BA) dysregulation is related to not only metabolic
diseases but also nonalcoholic fatty liver disease (NAFLD). We investigated whether …

METHODS: We collected stool samples from 287 participants from 5 hospitals in Japan
(healthy control [HC]: n= 88; mild fibrosis: n= 104; and advanced fibrosis group: n= 95) …

The perturbations in bile acids (BAs) in alcohol‐associated hepatitis (AH) and its
relationship to disease severity is not well defined. The aims of this study were to define (1) …

OBJECTIVES: The precipitous increase in nonalcoholic steatohepatitis (NASH) is
accompanied by a dramatic increase in the incidence of NASH-related hepatocellular …

Several animal studies have emphasized the role of gut microbiota in nonalcoholic fatty liver
disease (NAFLD). However, data about gut dysbiosis in human NAFLD remain scarce in the …

Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide, yet
the pathogenesis of NAFLD is only partially understood. Here, we investigated the role of the …