[HTML][HTML] Computational approaches to drug repurposing and pharmacology

RA Hodos, BA Kidd, S Khader… - … . Systems biology and …, 2016 - ncbi.nlm.nih.gov
Data in the biological, chemical, and clinical domains are accumulating at ever-increasing
rates and have the potential to accelerate and inform drug development in new ways …

In silico methods for drug repurposing and pharmacology

RA Hodos, BA Kidd, K Shameer… - … Systems Biology and …, 2016 - Wiley Online Library
Data in the biological, chemical, and clinical domains are accumulating at ever‐increasing
rates and have the potential to accelerate and inform drug development in new ways …

[HTML][HTML] On the Integration of In Silico Drug Design Methods for Drug Repurposing

E March-Vila, L Pinzi, N Sturm, A Tinivella… - Frontiers in …, 2017 - frontiersin.org
Drug repurposing has become an important branch of drug discovery. Several
computational approaches that help to uncover new repurposing opportunities and aid the …

Computational drug repurposing: current trends

B Karaman, W Sippl - Current medicinal chemistry, 2019 - ingentaconnect.com
Biomedical discovery has been reshaped upon the exploding digitization of data which can
be retrieved from a number of sources, ranging from clinical pharmacology to …

[图书][B] Computational methods for drug repurposing

Q Vanhaelen - 2019 - Springer
It is known that despite large R&D resources and expenses, the conventional drug discovery
process has become increasingly time-consuming and elicits a relatively high attrition rate …

An overview of computational methods, tools, servers, and databases for drug repurposing

S Sarvagalla, SB Syed, MS Coumar - In silico drug design, 2019 - Elsevier
Systematic investigation of older approved drugs for newer therapeutic indications helps in
reducing the time and money required to bring a medicine to the market, by circumventing …

[HTML][HTML] Trends and Applications in Computationally Driven Drug Repurposing

L Pinzi, G Rastelli - International Journal of Molecular Sciences, 2023 - mdpi.com
Drug repurposing is a widely used approach originally developed to aid in the identification
of new uses of already existing drugs outside the scope of the original medical indication [1] …

Computational methods for drug repurposing

P Sanseau, J Koehler - Briefings in bioinformatics, 2011 - academic.oup.com
Repurposing marketed drugs or compounds in development for alternative indications is not
new in the pharmaceutical industry. It is in fact quite common but it has been mostly done by …

[HTML][HTML] Drug repurposing: Iron in the fire for older drugs

HV Sonaye, RY Sheikh, CA Doifode - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Repositioning or" repurposing" of existing therapies for indications of alternative disease is
an attractive approach that can generate lower costs and require a shorter approval time …

Computational methods for drug repurposing

RV Rapicavoli, S Alaimo, A Ferro… - Computational Methods for …, 2022 - Springer
The wealth of knowledge and multi-omics data available in drug research has allowed the
rise of several computational methods in the drug discovery field, resulting in a novel and …