Neonicotinoids: mechanisms of systemic toxicity based on oxidative stress-mitochondrial damage

X Xu, X Wang, Y Yang, I Ares, M Martínez… - Archives of …, 2022 - Springer
Neonicotinoids are the most widely used pesticides in the world. However, research studies
have shown that it can affect the cognitive abilities and health of non-target bees and other …

Atrazine induces necroptosis by miR-181–5p targeting inflammation and glycometabolism in carp lymphocytes

Y Cui, K Yin, Y Gong, Y Qu, H Liu, H Lin - Fish & shellfish immunology, 2019 - Elsevier
Atrazine (ATR) causes environmental problems and damages the health of fish and aquatic
animals. MicroRNAs (miRNAs) play important roles in immune regulation. However, the …

Bisphenol A regulates cytochrome P450 1B1 through miR-27b-3p and induces carp lymphocyte oxidative stress leading to apoptosis

Q Liu, W Wang, Y Zhang, Y Cui, S Xu, S Li - Fish & shellfish immunology, 2020 - Elsevier
Bisphenol A (BPA) is an industrial raw material widely used in water bottles, medical devices
and food packaging, and is now ubiquitous in the environment. However, the effects of BPA …

Cadmium exposure triggers mitochondrial dysfunction and oxidative stress in chicken (Gallus gallus) kidney via mitochondrial UPR inhibition and Nrf2-mediated …

J Ge, C Zhang, YC Sun, Q Zhang, MW Lv, K Guo… - Science of the Total …, 2019 - Elsevier
Cadmium (Cd) is a widespread environmental pollutant that accumulates in living systems
and represents a significant global health hazard. Cd poses a toxicity threat to both human …

Inhibition of mitochondrial complex function—The hepatotoxicity mechanism of emodin based on quantitative proteomic analyses

L Lin, Y Liu, S Fu, C Qu, H Li, J Ni - Cells, 2019 - mdpi.com
Emodin is the main component of traditional Chinese medicines including rhubarb,
Polygonum multiflorum, and Polygonum cuspidatum. It has confirmed hepatotoxicity and …

Chronic hypoxia and Cu2+ exposure induce gill remodeling of largemouth bass through endoplasmic reticulum stress, mitochondrial damage and apoptosis

Q Liu, H Wang, J Ge, L Li, J Luo, K He, H Yan… - Aquatic Toxicology, 2023 - Elsevier
Hypoxia and Cu 2+ pollution often occur simultaneously in aquatic ecosystems and jointly
affect physiology of fish. As the respiratory and ion exchange tissue of fish, how gill responds …

Abamectin causes cardiac dysfunction in carp via inhibiting redox equilibrium and resulting in immune inflammatory response and programmed cell death

P Zhao, Y Wang, Q Yang, G Yu, F Ma… - Environmental Science and …, 2023 - Springer
This study aims to investigate the effects of environmentally relevant concentrations of
abamectin on the cardiac function of carp and the potential mechanisms. Here, male carp …

The two-way immunotoxicity in native fish induced by exudates of Microcystis aeruginosa: Immunostimulation and immunosuppression

S Zhao, X Chang, J Li, Y Zhu, X Pan, Z Hua… - Journal of Hazardous …, 2024 - Elsevier
Secondary metabolites of cyanobacterial blooms have caused serious risks to aquatic
animals. The immune system is an important barrier for fish against pollutants in aquatic …

Difenoconazole causes cardiotoxicity in common carp (Cyprinus carpio): Involvement of oxidative stress, inflammation, apoptosis and autophagy

J Wang, X Gao, F Liu, J Dong, P Zhao - Chemosphere, 2022 - Elsevier
Difenoconazole, a commonly used broad-spectrum triazole fungicide, is widely applied to
fish culture in paddy fields. Due to its high chemical stability, low biodegradability, and easy …

Thymoquinone alleviates mitochondrial viability and apoptosis in diclofenac-induced acute kidney injury (AKI) via regulating Mfn2 and miR-34a mRNA expressions

KS Hashem, AZ Abdelazem, MA Mohammed… - … Science and Pollution …, 2021 - Springer
The current study was prepared to assess the underlying mechanism of diclofenac (Diclo)-
stimulated renal oxidative damage (50 mg/kg/day for two consecutive days IP) and …