Pathophysiological roles of nitric oxide in inflammation

C Szabó - Nitric Oxide, 2000 - Elsevier
Publisher Summary Local and systemic inflammation is characterized by the overproduction
of nitric oxide (NO). In most instances, the source of this NO is the inducible isoform of NO …

Cytokine regulation of nitric oxide production

H Mühl, CA Dinarello - Nitric Oxide and Infection, 1999 - Springer
In numerous animal models associated with increased production of proinflam-matory
cytokines, nitric oxide (NO) has been shown to affect severity of disease. NO can influence …

Nitric oxide and inflammation

CC Wu - Current medicinal chemistry-anti-inflammatory & anti …, 2004 - ingentaconnect.com
Nitric oxide (NO) is a very labile molecule of ubiquitous significance in biological systems in
general. During the past two decades, NO has been recognized as one of the most versatile …

Direct and indirect modulation of the inducible nitric oxide synthase by nitric oxide: feedback mechanisms in inflammation

Y Vodovotz, MH Barccellos-Hoff - Nitric Oxide and Inflammation, 2001 - Springer
Cytokines are peptide hormones with a vast array of effects on growth, development,
immunity, and disease that are regulated in complex ways at the transcriptional, post …

III. A molecular prelude to intestinal inflammation

MJS Miller, M Sandoval - American Journal of Physiology …, 1999 - journals.physiology.org
Nitric oxide (NO) synthesis is markedly augmented in states of inflammation, largely due to
the expression of inducible nitric oxide synthase (iNOS). Although NO has anti-inflammatory …

Nitric oxide: what role does it play in inflammation and tissue destruction?

CH Evans - Agents and actions. Supplements, 1995 - europepmc.org
Large amount of nitric oxide (NO) are produced at sites of inflammation through the action of
inducible nitric oxide synthase (iNOS) present in both infiltrating leucocytes and activated …

Nitric oxide in inflammation and immune response

E Moilanen, H Vapaatalo - Annals of medicine, 1995 - Taylor & Francis
This short review deals with the role of a recently found signalling molecule, nitric oxide
(NO), in inflammatory and immune responses. NO regulates inflammatory erythema and …

I. Physiological chemistry of nitric oxide and its metabolites: implications in inflammation

MB Grisham, D Jourd'Heuil… - American Journal of …, 1999 - journals.physiology.org
The role of nitric oxide (NO) in inflammation represents one of the most studied yet
controversial subjects in physiology. A number of reports have demonstrated that NO …

Nitric oxide: a novel mediator of inflammation

RM Clancy, SB Abramson - Proceedings of the Society for …, 1995 - journals.sagepub.com
N itric oxide (NO), first identified as an endothelium-derived relaxation factor, is now
recognized to regulate the functions of many mammalian cells and tissues. Nitric oxide is …

Inducible nitric oxide synthase and inflammation

D Salvemini, MH Marino - Expert opinion on investigational drugs, 1998 - Taylor & Francis
Nitric oxide (NO), derived from L-arginine (L-Arg) by the enzyme nitric oxide synthase (NOS),
is involved in acute and chronic inflammatory events. In view of the complexity associated …