Summary Alpha‐1 antitrypsin (A1AT) is a serine anti‐protease produced chiefly by the liver.
A1AT deficiency is a genetic disorder characterized by serum levels of less than 11 μmol/L …

ABSTRACT α1-antitrypsin (α1AT) deficiency is a common lethal hereditary disorder of white
persons of European descent. The condition is characterized by reduced serum levels of α …

Since the condition was first described four decades ago, alpha-1-antitrypsin (A1AT)
deficiency has served as a model for other disease processes. A1AT is the archetypal serpin …

Abstract Alpha-1-antitrypsin (AAT) is an acute phase secretory glycoprotein that inhibits
neutrophil proteases like elastase and is considered as the archetype of a family of …

Objective To review the topic of alpha-1 antitrypsin (AAT) deficiency. Method Narrative
literature review. Results Much work has been carried out on this condition with many …

α1-Antitrypsin (α1AT) deficiency is characterized by reduced serum levels of α1AT and a risk
for the development of emphysema and liver disease. However, whereas there is an …

Alpha-1-antitrypsin (A1AT) deficiency is an autosomal hereditary disorder associated with a
major reduction in serum A1AT levels. Clinically, A1AT deficiency is associated with …

Alpha-1-antitrypsin (α1-AT) deficiency is a well known cause of emphysema in adults. A
subgroup of deficient individuals develops liver injury during infancy and childhood. In fact, it …

α1-Antitrypsin deficiency • 3: Clinical manifestations and natural history | Thorax Skip to main
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Providing a broad overview of basic and clinical aspects of alpha 1-antitrypsin (a 1AT)
deficiency, this up-to-date reference discusses the complex pathobiological processes …