Background: Chronic depressive disorders are common, accounting for approximately one-
third of all cases of depression and posing a major public health problem. In the past …

Major depressive disorder (MDD) is defined in a manner that overlooks the heterogeneous
nature and high rate of comorbidity. The similitude between depressive symptomatology and …

Background: The Canadian Psychiatric Association and the Canadian Network for Mood
and Anxiety Treatments partnered to produce clinical guidelines for psychiatrists for the …

Importance Approximately 9% of US adults experience major depression each year, with a
lifetime prevalence of approximately 17% for men and 30% for women. Observations Major …

An update is available for this article. Background: Primary care patients and clinicians may
prefer alternative options to second-generation antidepressants for major depressive …

Об актуальности проблемы депрессий свидетельствуют эпидемиологические данные:
распространенность расстройств депрессивного спектра в населении стран Европы и …

Background: Depressive disorders are persistent, recurring illnesses that cause great
suffering for patients and their families. Purpose: To evaluate the benefits and adverse …

Antidepressants lead to improvement in about 70% of unselected patients with a depressive
syndrome. However, many of these patients would also improve with the passage of time …

Objectives Depressive disorders are persistent, recurring illnesses that impose enormous
personal suffering on individuals and their families. Major depression alone is estimated as …

Background Although previous meta-analyses have examined effects of antidepressants,
psychotherapy, and alternative therapies for depression, the efficacy of these treatments …