Abstract Background The Lyon Consensus proposed a hierarchical approach to GERD
diagnosis based on conventional and new impedance-pH metrics, namely acid exposure …

Background Mean nocturnal baseline impedance (MNBI) and post-reflux swallow-induced
peristaltic wave (PSPW) index are able to increase the diagnostic yield of impedance-pH …

Summary Background The Lyon Consensus delineates impedance‐pH parameters that can
demonstrate/exclude gastro‐oesophageal reflux disease (GERD). In patients with acid …

Background Impedance‐pH monitoring allows evaluation of esophageal chemical
clearance, a response to reflux elicited by the esophago‐salivary reflex, by means of the …

Gastroesophageal reflux disease (GERD) is a complex disorder with heterogeneous
symptoms and a multifaceted pathogenetic basis, which prevent a simple diagnostic …

Background On‐therapy impedance‐pH monitoring is recommended in patients with
documented GERD and PPI‐refractory heartburn in order to establish whether the …

Background Impairment of esophageal mucosal integrity as assessed by low mean
nocturnal baseline impedance (MNBI) measured in the distal esophagus increases the …

Objective To validate Lyon Consensus criteria for diagnosing gastro-oesophageal reflux
disease (GORD) by reflux monitoring. Design Manual review of impedance-pH tracings from …

Gastro-esophageal reflux disease (GERD) occurs in about 25% of the general population.
The complexity of the disease and the multiplicity of its clinical manifestations impair the …

Center for Gastroenterological Research, Catholic University of Leuven, Leuven, Belgium
tion of patients with GERD symptoms, including typical symptoms in patients off PPIs …