High potassium intake is known to attenuate hypertension, glomerular lesion, ischemic
damage, and stroke-associated death. Our recent studies showed that expression of …

The kallikrein-kinin system (KKS) is involved in the regulation of blood pressure and in the
sodium and water excretion. In humans, the KKS is divided functionally into a plasma KKS …

The tissue kallikrein-kinin system has been recognized as a paracrine and/or autocrine
hormonal system that regulates arterial pressure, renal hemodynamics, and electrolyte …

Tissue kallikrein cleaves low-molecular-weight (low-M (r)) kininogen to produce the
vasoactive kinin peptide. It has been suggested that hypertensive patients with low urinary …

We evaluated the blood pressure response to chronic salt loading in a rat strain inbred for
low urinary kallikrein excretion. Low-kallikrein rats showed greater systolic blood pressure …

The mechanisms involved in the postnatal induction of renal kallikrein gene transcription
and enzymatic activity are unknown. The present study was designed to test the hypothesis …

The albumin overload model induces proteinuria and tubulointersitial damage, followed by
hypertension when rats are exposed to a hypersodic diet. To understand the effect of kinin …

Intravenous infusion of a high-K+ solution (67.5 mM KCl, 67.5 mM NaCl) to anesthetized rats
increased urine volume by 47.6% after 60 min, compared with infusion of a Na+ solution …

In a previous study, we characterized a B2-kinin-binding site in rat glomerular membranes.
We have now investigated the density and affinity of this binding site for bradykinin (BK) in …

CARRETERO, OSCAR A., AND ALFONSO G. SCICLI. The renaZ kahkreinkinin system. Am.
J. Physiol. 238 (Renal Fluid Electrolyte Physiol. 7): F247-F255, 1980.-Kallikreins are …