A gas chromatographic—mass spectrometric method is described for the determination of
plasma selegiline. Tetradeuteroselegiline was synthesized and served as the internal …

This report describes a sensitive and specific high-performance liquid chromatography-
atmospheric pressure chemical ionization-tandem mass spectrometry method for the …

Selegiline (formerly known as L-deprenyl) is a monoamino-oxidase-B inhibitor, which
decreases dopamine degradation at the neuronal level and is therefore used as an adjuvant …

A method for the simultaneous determination of selegiline and its metabolite,
desmethylselegiline, in human whole blood and urine is presented. The method, which …

A bioavailability study of 2 different selegiline preparations were conducted in 20 healthy
volunteers to test the bioequivalence. Almost no bioavailability study of selegiline has been …

A high-performance liquid chromatographic (HPLC) method with fluorescence detection was
developed for the determination in human plasma of the three main metabolites of selegiline …

Selegiline is best known as an irreversible inhibitor of monoamine oxidase (MAO), an
intracellular enzyme associated with the outer membrane of mitochondria. The purpose of …

1. The metabolism of selegiline (SG) has been studied by investigating the timecourse of
urinary excretion of SG and its metabolites using high-performance liquid chromatography …

A liquid chromatographic method has been developed for determination of selegiline
hydrochloride and related substances in drug raw material and tablet formulations. The …

The stereoselective analysis of selegiline metabolites in human urine and plasma by gas
chromatography using the chiral column with the non-chiral reagent was investigated for the …