Suppression of cell invasion and migration by propofol are involved in down-regulating matrix metalloproteinase-2 and p38 MAPK signaling in A549 human lung …

KC Wu, ST Yang, TC Hsia, JS Yang… - Anticancer …, 2012 - ar.iiarjournals.org
Metastasis is a major cause of death of patients with malignant tumors. Matrix
metalloproteinases (MMPs) are important for the migration and invasion of various types of …

Nicotine stimulates human lung cancer cell growth by inducing fibronectin expression

Y Zheng, JD Ritzenthaler, J Roman… - American journal of …, 2007 - atsjournals.org
The mechanisms by which tobacco promotes lung cancer remain incompletely understood.
Herein, we report that nicotine, a major component of tobacco, promotes the proliferation of …

Activation of 5-lipoxygenase is required for nicotine mediated epithelial–mesenchymal transition and tumor cell growth

VY Shin, HC Jin, EKO Ng, JJY Sung, KM Chu, CH Cho - Cancer Letters, 2010 - Elsevier
Nicotine is shown to be one of the carcinogenic agents for gastric cancer. Perturbation of
epithelial–mesenchymal transition (EMT) results in loss of intracellular adhesions leading to …

FoxQ1 overexpression influences poor prognosis in non-small cell lung cancer, associates with the phenomenon of EMT

J Feng, X Zhang, H Zhu, X Wang, S Ni, J Huang - PloS one, 2012 - journals.plos.org
Background We determined the expression of forkhead box Q1 (FoxQ1), E-cadherin (E-cad),
Mucin 1 (MUC1), vimentin (VIM) and S100 calcium binding protein A4 (S100A4), all …

Coexpression of Oct4 and Nanog Enhances Malignancy in Lung Adenocarcinoma by Inducing Cancer Stem Cell–Like Properties and Epithelial–Mesenchymal …

SH Chiou, ML Wang, YT Chou, CJ Chen, CF Hong… - Cancer research, 2010 - AACR
Abstract Epithelial–mesenchymal transition (EMT), a critical process of cancer invasion and
metastasis, is associated with stemness property of cancer cells. Though Oct4 and Nanog …

Morphine induces expression of platelet-derived growth factor in human brain microvascular endothelial cells: implication for vascular permeability

H Wen, Y Lu, H Yao, S Buch - PloS one, 2011 - journals.plos.org
Despite the advent of antiretroviral therapy, complications of HIV-1 infection with concurrent
drug abuse are an emerging problem. Morphine, often abused by HIV-infected patients, is …

Urolithin A inhibits epithelial–mesenchymal transition in lung cancer cells via P53-Mdm2-snail pathway

F Cheng, J Dou, Y Zhang, X Wang, H Wei… - OncoTargets and …, 2021 - Taylor & Francis
Purpose The epithelial-to-mesenchymal transition (EMT) is a fundamental process in tumor
progression that endows cancer cells with migratory and invasive potential. Snail, a zinc …

[HTML][HTML] Epithelial–mesenchymal transition promotes SOX2 and NANOG expression in bladder cancer

T Migita, A Ueda, T Ohishi, M Hatano, H Seimiya… - Laboratory …, 2017 - Elsevier
Bladder cancer is the most common malignant tumor of the urothelium and is classified into
non-muscle-invasive bladder cancer (NMIBC) and muscle-invasive bladder cancer (MIBC) …