[PDF][PDF] Aldosterone upregulates chemerin via chemokinelike receptor 1-Rho-ROCK-JNK signaling in cardiac fibroblasts

Y Wang, X Jin, L Qiao, Y Li, R Yang, M Wang… - Int J Clin Exp …, 2017 - e-century.us
Chemerin is a novel adipokine that affects inflammation, insulin resistance, metabolic
syndrome, and cardiovascular diseases. Nonetheless, it is unclear whether chemerin is …

Chemerin Promotes Proliferation of Cardiac Fibroblasts via CMKLR1/PI3k/Akt/NF-κB Signaling Pathway

R Cai, R Cao, Y Liu, N Zhang, Y Zhang, Y Wang - 2024 - researchsquare.com
Background: Chemerin expression has been documented to be increased in patients with
heart failure (HF), animal models of myocardial fibrosis (MF), and proliferation of cardiac …

Chemerin induces insulin resistance in rat cardiomyocytes in part through the ERK1/2 signaling pathway

R Zhang, S Liu, B Guo, L Chang, Y Li - Pharmacology, 2015 - karger.com
Aims: Chemerin is a novel adipokine that is closely associated with cardiovascular diseases
and glucose homeostasis. This study aimed to investigate the effects of chemerin on insulin …

Effects of aldosterone on chemerin expression and secretion in 3t3-l1 adipocytes

J Ma, F Sun, J Wang, H Jiang, J Lu… - Experimental and …, 2018 - thieme-connect.com
Aldosterone plays a pivotal role in the pathogenesis of metabolic syndrome and
cardiovascular disease; however, the underlying mechanisms have not been clarified …

[HTML][HTML] The adipokine chemerin induces apoptosis in cardiomyocytes

D Rodríguez-Penas, S Feijóo-Bandín… - Cellular Physiology and …, 2015 - karger.com
Background: The adipokine chemerin has been associated with cardiovascular disease. We
investigated the effects of chemerin on viability and intracellular signalling in murine …

Chemerin-9 stimulates migration in rat cardiac fibroblasts in vitro

A Yamamoto, A Sagara, K Otani, M Okada… - European Journal of …, 2021 - Elsevier
Since chemerin is an adipocytokine whose concentration in blood increases in the subjects
with various cardiac diseases, chemerin may be involved in pathogenesis of cardiac …

[HTML][HTML] Effects of chemerin/CMKLR1 in obesity-induced hypertension and potential mechanism

C Weng, Z Shen, X Li, W Jiang, L Peng… - American Journal of …, 2017 - ncbi.nlm.nih.gov
Background: Obesity-induced hypertension (OIH) has a high morbidity and mortality, and its
prevention and treatment has been a major challenge in clinical practice. Chemerin is a …

Chemerin is a novel adipocyte-derived factor inducing insulin resistance in primary human skeletal muscle cells

H Sell, J Laurencikiene, A Taube, K Eckardt… - Diabetes, 2009 - Am Diabetes Assoc
OBJECTIVE Chemerin is an adipokine that affects adipogenesis and glucose homeostasis
in adipocytes and increases with BMI in humans. This study was aimed at investigating the …

Chemerin regulates proliferation and differentiation of myoblast cells via ERK1/2 and mTOR signaling pathways

H Yang, F Li, X Kong, X Yuan, W Wang, R Huang, T Li… - Cytokine, 2012 - Elsevier
Obesity in human is an alarming major public health crisis worldwide and insulin resistance
is a hallmark of it. The negative cross-talk between skeletal muscle and adipose tissue …

Renal chemerin expression is induced in models of hypertensive nephropathy and glomerulonephritis and correlates with markers of inflammation and fibrosis

A Mocker, KF Hilgers, N Cordasic, R Wachtveitl… - International journal of …, 2019 - mdpi.com
Chemerin and its receptor, chemokine-like receptor 1 (CmklR1), are associated with
chemotaxis, inflammation, and endothelial function, especially in metabolic syndrome …