TYROSINASE AND γ‐GLUTAMYL TRANSPEPTIDASE IN 5‐S‐CYSTEINYLDOPA GENESIS WITHIN MELANOTIC AND AMELANOTIC MELANOMAS
M Mojamdar, M Ichihashi… - The Journal of …, 1982 - Wiley Online Library
The roles of tyrosinase and γ‐glutamyl transpeptidase (γ‐GTP) in 5‐S‐cysteinyldopa (5‐S‐
CD) genesis in melanotic and amelanotic melanoma cells has been investigated in vitro and …
CD) genesis in melanotic and amelanotic melanoma cells has been investigated in vitro and …
γ-Glutamyl transpeptidase, tyrosinase, and 5-S-cysteinyldopa production in melanoma cells
M Mojamdar, M Ichihashi, Y Mishima - Journal of investigative dermatology, 1983 - Elsevier
The distribution of γ-glutamyl transpeptidase (γ-GTP), tyrosinase, and 5-S-cysteinyldopa (5-
S-CD) within melanoma cells has been studied in vitro as well as in vivo. Sodium periodate …
S-CD) within melanoma cells has been studied in vitro as well as in vivo. Sodium periodate …
Effect of dopa-loading on glutathione metabolising enzymes and tyrosinase in relation to 5-S-cysteinyl-dopa genesis in cultured B-16 melanoma cells
AK Chakraborty, M Ichihashi, Y Mishima - Journal of Dermatological …, 1991 - Elsevier
The effect of DOPA and glutathione (GSH) on enzyme systems for 5-S-cysteinyl-DOPA
(5SCD) genesis in murine melanoma cells cultured in tyrosine-and cystine-free medium …
(5SCD) genesis in murine melanoma cells cultured in tyrosine-and cystine-free medium …
Effect of DOPA-loading on glutathione-dependent 5-S-cysteinyldopa genesis in melanoma cells in vitro
M Mojamdar, M Ichihashi, Y Mishima - Journal of Investigative Dermatology, 1982 - Elsevier
The effect of dopa, cysteine, and glutathione on 5-S-cysteinyldopa (5-S-CD) genesis in
melanoma cells cultured in normal and tyrosine-and cysteine-free media has been studied …
melanoma cells cultured in normal and tyrosine-and cysteine-free media has been studied …
Effects of L‐glutamine on Tyrosinase and γ‐glutamyl Transpeptidase of B‐16 Melanoma Cells in Culture
C Chakraborty, S Hatta, M Ichihashi… - The Journal of …, 1988 - Wiley Online Library
Omission of L‐glutamine (Gln) from the culture medium decreases tyrosinase activity and
increases γ‐GTP activity in cultured melanotic B‐16 melanoma cells; inclusion of this amino …
increases γ‐GTP activity in cultured melanotic B‐16 melanoma cells; inclusion of this amino …
Melanin-related biochemistry of IGR 1 human melanoma cells
E Karg, G Odh, E Rosengren, A Wittbjer… - Melanoma …, 1991 - journals.lww.com
Cultured melanoma cells have been of great value in the study of pigment metabolism. IGR
1 human melanoma cells, established by Dr Christian Aubert, produce melanin in large …
1 human melanoma cells, established by Dr Christian Aubert, produce melanin in large …
Modulation of 5-S-cysteinyldopa formation by tyrosinase activity and intracellular thiols in human melanoma cells
M Benathan - Melanoma research, 1996 - journals.lww.com
Abstract The catechol 5-S-cysteinyldopa (5-S-CD) is produced in large amounts in
metastatic malignant melanoma. To further understand the mechanism of formation of 5 …
metastatic malignant melanoma. To further understand the mechanism of formation of 5 …
Theophylline and melanocyte-stimulating hormone effects on gamma-glutamyl transpeptidase and DOPA reactions in cultured melanoma cells
F Hu - Journal of Investigative Dermatology, 1982 - Elsevier
Gamma-glutamyl transpeptidase (GGT), an enzyme of the γ-glutamyl cycle, was
demonstrated in 3 of 6 cell lines derived from a single B16 murine melanoma. Its activity in …
demonstrated in 3 of 6 cell lines derived from a single B16 murine melanoma. Its activity in …
Dopaquinone addition products in cultured human melanoma cells.
R Carstam, C Hansson, C Lindbladh… - Acta dermato …, 1987 - europepmc.org
The concentrations of dopa, cysteinyldopas, 5-S-glutathionyldopa, gamma-glutamyl-5-S-
cysteinyldopa and 5-S-cysteinylglycinedopa, were analysed in homogenates of cultured …
cysteinyldopa and 5-S-cysteinylglycinedopa, were analysed in homogenates of cultured …
Inability of murine melanoma melanosomal" tyrosinase"(L-dopa oxidase) to oxidize tyrosine to melanin in polyacrylamide gel systems
LM Edelstein, N Cariglia, MR Okun, RP Patel… - Journal of Investigative …, 1975 - Elsevier
Melanosoinal “tyrosinase”(L-dopa oxidase) was isolated from trypsin digests of B-16 mouse
melanoma melanosomes, using polyacrylamide gel disc electrophoresis. The enzyme was …
melanoma melanosomes, using polyacrylamide gel disc electrophoresis. The enzyme was …