Autophagic Cell Death in Dictyostelium Requires the Receptor Histidine Kinase DhkM

C Giusti, MF Luciani, S Ravens, A Gillet… - Molecular biology of …, 2010 - Am Soc Cell Biol
Dictyostelium constitutes a genetically tractable model for the analysis of autophagic cell
death (ACD). During ACD, Dictyostelium cells first transform into paddle cells and then …

[HTML][HTML] Autophagic cell death: analysis in Dictyostelium

C Giusti, E Tresse, MF Luciani, P Golstein - Biochimica et Biophysica Acta …, 2009 - Elsevier
Autophagic cell death (ACD) can be operationally described as cell death with an
autophagic component. While most molecular bases of this autophagic component are …

Autophagy and autophagic cell death in Dictyostelium

E Tresse, C Giusti, A Kosta, MF Luciani… - Methods in enzymology, 2008 - Elsevier
Autophagic cell death can be conveniently studied in Dictyostelium discoideum, an
exceptionally favorable model not only because of its well‐known genetic and experimental …

Analysis of autophagic and necrotic cell death in Dictyostelium

C Giusti, A Kosta, D Lam, E Tresse, MF Luciani… - Methods in …, 2008 - Elsevier
Non‐apoptotic cell death types can be conveniently studied in Dictyostelium discoideum, an
exceptionally favorable model not only because of its well‐known genetic and experimental …

A UDP-glucose derivative is required for vacuolar autophagic cell death

E Tresse, A Kosta, C Giusti, MF Luciani, P Golstein - Autophagy, 2008 - Taylor & Francis
Autophagic cell death in Dictyostelium can be dissociated into a starvation-induced
sensitization stage and a death induction stage. A UDP-glucose pyrophosphorylase (ugpB) …

A second signal for autophagic cell death?

C Giusti, MF Luciani, P Golstein - Autophagy, 2010 - Taylor & Francis
Dictyostelium cells in monolayers in vitro lend themselves well to a study of autophagic cell
death (ACD). There is no apoptosis machinery in the protist Dictyostelium, no caspase nor …

From autophagic to necrotic cell death in Dictyostelium

E Tresse, A Kosta, MF Luciani, P Golstein - Seminars in cancer biology, 2007 - Elsevier
Among unusual models to study cell death mechanisms, the protist Dictyostelium is
remarkable because of its strategic phylogenetic position, with early emergence among …

Atg1 allows second-signaled autophagic cell death in Dictyostelium

MF Luciani, C Giusti, B Harms, Y Oshima, H Kikuchi… - Autophagy, 2011 - Taylor & Francis
We investigated the role of Atg1 in autophagic cell death (ACD) in a Dictyostelium
monolayer model. The model is especially propitious, not only because of genetic tractability …

A specific pathway inducing autophagic cell death is marked by an IP3R mutation

D Lam, P Golstein - Autophagy, 2008 - Taylor & Francis
Three main advantages make Dictyostelium a very favorable model to study the induction of
autophagic cell death in vitro. First, its small, sequenced and haploid genome facilitates …

How to Assess and Study Cell Death in Dictyostelium discoideum

A Kosta, C Laporte, D Lam, E Tresse… - Dictyostelium …, 2006 - Springer
In this chapter, we describe how to conveniently demonstrate, assess, and study cell death
in Dictyostelium through simple cell culture, clonogenic tests, and photonic (with the help of …