The chromosome band 11q23 is a common target region of chromosomal translocation in
different types of leukemia, including infantile leukemia and therapy-related leukemia. The …

We described the clinical features and outcomes for 63 adult patients with acute myeloid
leukemia (AML) with a translocation involving the 11q23 locus (MLL) who were treated at …

A 79-year-old female presented with acute myeloblastic leukemia without maturation.
Cytogenetic studies showed a previously undescribed abnormality of t (7; 11)(q36; q13). The …

The human JAK2 gene is targeted by three types of genetic lesions playing a role in the
pathogenesis of hematologic malignancies. These include point mutations (eg exon 12–14 …

Translocation (10; 17)(p13-15; q12-21) in acute leukemia is rarely reported in the literature.
Here, we present both a novel t (10; 17) case study and a review of relevant literature on t …

A 35-year-old female patient was diagnosed with acute myeloid leukemia with multiple
genetic aberrations [48 XX, del (3)(q21),+ 6, t (11; 15)(q23; q15),+ 21] including an …

The translocation (8; 21)(q22; q22) is a frequent karyotypic abnormality in acute
myelogenous leukemia (AML). Most cases of AML with t (8; 21) show an M2 phenotype …

We report clinical, immunologic, and cytogenetic characteristics of six patients with at (1;
19)(q23; p13) that was balanced in one case and of the unbalanced type [− 19, der (19) t (1; …

Chromosome 11 abnormalities are found in many hematological malignancies. In acute
myeloid leukemia (AML), a proto‐oncogene MLL (11q23. 3) is frequently altered. However …

Translocations involving 11q23 are considered synonymous with rearrangements of the
MLL gene. They are usually associated with B-lineage acute lymphoblastic leukemia (ALL) …