Background Ovarian cancer is one of the most common gynecological malignancies. Due to
the absence of effective screening methods, ovarian cancer is usually diagnosed at late …

Introduction Ovarian cancer is the third most common cancer among Indian women. The
data on the hereditary predisposition of these cancers and the clinical outcomes of those …

In India, the incidence of breast cancer accounted for 1, 78,361 cases, whereas ovarian
cancer accounts for 45,701 cases, according to Globocan Report 2020. These cancers are …

Background The worldwide reported prevalence of germline pathogenic BRCA1 and
BRCA2 mutations in ovarian cancer patients is 17%(3-27%) and that of variants of uncertain …

Background: The prevalence of pathogenic BRCA mutations in high hereditary risk breast
cancer patients (pts) in ethnic Lebanese Arab women was 5.6% in a study published in …

Background Patients with germline mutations in BRCA1/2 are at high risk of developing
ovarian cancer (OC). However, genetic testing for BRCA1/2 mutations is still not a routine …

Clinical criteria for genetic testing of genes other than BRCA1/2 in epithelial ovarian cancer
(EOC) still do not exist. We assessed the frequency and predictors of deleterious mutations …

Background Ovarian cancer is the fifth most common cause of cancer death for women in
the UK. Up to 18% of cases can be attributed to germline mutations in BRCA1 and BRCA2 …

Objective Routine genetic testing for ovarian cancer and identification of germline mutations
can help improve early detection of cancer as well as guide treatment. Knowledge of genetic …

BACKGROUND Genetic testing is widely recommended for all epithelial ovarian cancer
(EOC) patients. However, an increased probability of identifying germline mutations has …