Effects of cetyltrimethylammonium bromide on the toxicity of gold nanorods both in vitro and in vivo: molecular origin of cytotoxicity and inflammation

YP Jia, K Shi, JF Liao, JR Peng, Y Hao, Y Qu… - Small …, 2020 - Wiley Online Library
The safety issues and immunological effects of nanosized materials have drawn
considerable attention. Gold nanorods (Au NRs) have promising applications in biomedical …

Surface chemistry but not aspect ratio mediates the biological toxicity of gold nanorods in vitro and in vivo

J Wan, JH Wang, T Liu, Z Xie, XF Yu, W Li - Scientific reports, 2015 - nature.com
Gold nanorods are a promising nanoscale material in clinical diagnosis and treatment. The
physicochemical properties of GNRs, including size, shape and surface features, are crucial …

In vitro cytotoxicity of gold nanorods in A549 cells

Y Tang, Y Shen, L Huang, G Lv, C Lei, X Fan… - Environmental …, 2015 - Elsevier
Gold nanoparticles, which have unique physicochemical characteristics, are being used for
an increasingly wide range of applications in biomedical research. In this study, gold …

Revealing silver cytotoxicity using Au nanorods/Ag shell nanostructures: disrupting cell membrane and causing apoptosis through oxidative damage

X Cheng, W Zhang, Y Ji, J Meng, H Guo, J Liu, X Wu… - RSC …, 2013 - pubs.rsc.org
Silver nanoparticles (NPs) have been widely explored as antibacterial and antifungal agents
in households, cosmetics, food packaging, medical devices and even various wound care …

Effect of size, shape, and surface modification on cytotoxicity of gold nanoparticles to human HEp‐2 and canine MDCK cells

Y Zhang, D Xu, W Li, J Yu, Y Chen - Journal of Nanomaterials, 2012 - Wiley Online Library
There have been increasing interests in applying gold nanoparticles in biological research,
drug delivery, and therapy. As the interaction of gold nanoparticles with cells relies on …

Surface chemistry of gold nanorods: origin of cell membrane damage and cytotoxicity

L Wang, X Jiang, Y Ji, R Bai, Y Zhao, X Wu, C Chen - Nanoscale, 2013 - pubs.rsc.org
We investigated how surface chemistry influences the interaction between gold nanorods
(AuNRs) and cell membranes and the subsequent cytotoxicity arising from them in a serum …

Gold nanoparticles induce cytotoxicity in the alveolar type-II cell lines A549 and NCIH441

C Uboldi, D Bonacchi, G Lorenzi, MI Hermanns… - Particle and fibre …, 2009 - Springer
Background During the last years engineered nanoparticles (NPs) have been extensively
used in different technologies and consequently many questions have arisen about the risk …

Surface chemistry and aspect ratio mediated cellular uptake of Au nanorods

Y Qiu, Y Liu, L Wang, L Xu, R Bai, Y Ji, X Wu, Y Zhao… - Biomaterials, 2010 - Elsevier
Gold nanorods (Au NRs) have been recognized as promising materials for biomedical
applications, like sensing, imaging, gene and drug delivery and therapy, but their …

The in vitro and in vivo toxicity of gold nanoparticles

YP Jia, BY Ma, XW Wei, ZY Qian - Chinese Chemical Letters, 2017 - Elsevier
Gold nanoparticles, owing to their unique physicochemical and optical properties, well-
established synthetic methods and easy modifications, have been widely used in biomedical …

Gold-based nanospheres and nanorods particles used as theranostic agents: An in vitro and in vivo toxicology studies

J Cancino-Bernardi, VS Marangoni, JCF Besson… - Chemosphere, 2018 - Elsevier
The adverse effect of gold-based nanoparticles is still an open question since it depends on
several factors as shape, surface charge or route of administration. In this study, we …