Combining 2D angiogenesis and 3D osteosarcoma microtissues to improve vascularization
H Chaddad, S Kuchler-Bopp, G Fuhrmann… - Experimental cell …, 2017 - Elsevier
Angiogenesis is now well known for being involved in tumor progression, aggressiveness,
emergence of metastases, and also resistance to cancer therapies. In this study, to better …
emergence of metastases, and also resistance to cancer therapies. In this study, to better …
The Dominant Role of IL-8 as an Angiogenic Driver in a Three-Dimensional Physiological Tumor Construct for Drug Testing
The induction of angiogenesis and the promotion of tumor growth and invasiveness are
processes critical to metastasis, and are dependent on reciprocal interactions between …
processes critical to metastasis, and are dependent on reciprocal interactions between …
Bioengineered three‐dimensional co‐culture of cancer cells and endothelial cells: A model system for dual analysis of tumor growth and angiogenesis
Angiogenesis marks the transformation of a benign local tumor into a life‐threatening
disease. Many in vitro assays are available on two‐dimensional (2D) platforms, however …
disease. Many in vitro assays are available on two‐dimensional (2D) platforms, however …
[HTML][HTML] Development of a 3D angiogenesis model to study tumour–endothelial cell interactions and the effects of anti-angiogenic drugs
A Amann, M Zwierzina, S Koeck, G Gamerith… - Scientific reports, 2017 - nature.com
The tumour microenvironment and tumour angiogenesis play a critical role in the
development and therapy of many cancers, but in vitro models reflecting these …
development and therapy of many cancers, but in vitro models reflecting these …
Oxygen-controlled three-dimensional cultures to analyze tumor angiogenesis
Tumor angiogenesis is controlled by the integrated action of physicochemical and biological
cues; however, the individual contributions of these cues are not well understood. We have …
cues; however, the individual contributions of these cues are not well understood. We have …
Differential angiogenic potential of 3-dimension spheroid of HNSCC cells in mouse xenograft
The experimental animal model is still essential in the development of new anticancer drugs.
We characterized mouse tumors derived from two-dimensional (2D) monolayer cells or three …
We characterized mouse tumors derived from two-dimensional (2D) monolayer cells or three …
Translating tissue engineering technology platforms into cancer research
Introduction• History of tissue engineering• Physiological and structural aspects of 2D versus
3D culture in cancer research• State of the art of 3D culture systems in cancer research• New …
3D culture in cancer research• State of the art of 3D culture systems in cancer research• New …
Lung adenocarcinoma cell responses in a 3D in vitro tumor angiogenesis model correlate with metastatic capacity
Many tools from the field of tissue engineering can be used to develop novel model systems
to study cancer. We have utilized biomimetic synthetic hydrogels, based on poly (ethylene …
to study cancer. We have utilized biomimetic synthetic hydrogels, based on poly (ethylene …
Tissue-engineered 3D tumor angiogenesis models: potential technologies for anti-cancer drug discovery
Angiogenesis is indispensable for solid tumor expansion, and thus it has become a major
target of cancer research and anti-cancer therapies. Deciphering the arcane actions of …
target of cancer research and anti-cancer therapies. Deciphering the arcane actions of …
Evaluation of Three-Dimensional in Vitro Models to Study Tumor Angiogenesis
The tumor microenvironment is a key factor in the progression and metastasis of cancer, the
complexity of which is not reproducible using two-dimensional (2D) culture models. While …
complexity of which is not reproducible using two-dimensional (2D) culture models. While …