Background and aims: The role of statins in unruptured intracranial aneurysm (UIA) growth
and rupture remains ambiguous. This study sought to determine whether atorvastatin is …

Several basic experimental studies have demonstrated that statins have beneficial effects for
intracranial aneurysm (IA). Clinical studies on unruptured IAs, however, remain limited to …

AbsTrACT background and purpose A large proportion of patients with unruptured
intracranial aneurysm (IA) are not suitable for surgical clipping and endovascular treatment …

Background Statins have been shown to decrease aneurysm progression and rupture in two
experimental settings: animals with cerebral aneurysm and humans with abdominal aortic …

Background Acetylsalicylic acid (ASA) and statins have been identified as potentially
reducing the risk of intracranial aneurysms (IA) rupture. We aim to determine the effect of this …

Background and purpose Establishment of drug therapy to prevent rupture of unruptured
intracranial aneurysms (IAs) is needed. Previous human and animal studies have gradually …

Background and Purpose—Growing evidence from experimental animal models and clinical
studies suggests the protective effect of statin use against rupture of intracranial aneurysms; …

Statins have been suggested in previous studies to play a protective role in experimental
cerebral aneurysm (CA) models; however, no evidence supports that the application of …

Inflammation plays an integral role in the formation, growth, and progression to rupture of
unruptured intracranial aneurysms. Aneurysm wall enhancement (AWE) in high-resolution …

Background Recent reports have showed that some statins have protective effects in
experimental cerebral aneurysm models. We conducted a case–control study to investigate …