Adult skeletal muscle stem cells differentiate into endothelial lineage and ameliorate renal dysfunction after acute ischemia

M Arriero, SV Brodsky, O Gealekman… - American Journal …, 2004 - journals.physiology.org
We previously demonstrated that endothelial cells are severely damaged during renal
ischemia-reperfusion and that transplantation of adult human endothelial cells into athymic …

[HTML][HTML] Kidney-derived mesenchymal stem cells contribute to vasculogenesis, angiogenesis and endothelial repair

J Chen, HC Park, F Addabbo, J Ni, E Pelger, H Li… - Kidney international, 2008 - Elsevier
We isolated a clonal cell line (4E) from kidneys of mice expressing green fluorescent protein
controlled by the endothelial-specific Tie2 promoter. When grown in a three-dimensional …

Vasculotropic, paracrine actions of infused mesenchymal stem cells are important to the recovery from acute kidney injury

F Togel, K Weiss, Y Yang, Z Hu… - American Journal …, 2007 - journals.physiology.org
Acute kidney injury (AKI) is a major clinical problem in which a critical vascular,
pathophysiological component is recognized. We demonstrated previously that …

The regenerative potential of stem cells in acute renal failure

M Morigi, A Benigni, G Remuzzi… - Cell …, 2006 - journals.sagepub.com
Adult stem cells have been characterized in several tissues as a subpopulation of cells able
to maintain, generate, and replace terminally differentiated cells in response to physiological …

Amelioration of Acute Renal Failure by Stem Cell Therapy—Paracrine Secretion Versus Transdifferentiation into Resident Cells: Administered Mesenchymal Stem …

F Togel, Z Hu, K Weiss, J Isaac, C Lange… - Journal of the …, 2005 - journals.lww.com
Although the kidney has been suspected, though not definitively proven, to contain organ-
specific pluripotent stem cells, their role in regeneration after renal injury is uncertain (1–3) …

[HTML][HTML] Stem cells for kidney repair: useful tool for acute renal failure?

T Yokoo, T Kawamura, E Kobayashi - Kidney international, 2008 - Elsevier
Several cell types isolated from adult tissues have been reported to differentiate into mature
kidney cells that may participate in renal repair after systemic administration. Chen et al …

Bone marrow–derived endothelial progenitor cells and endothelial cells may contribute to endothelial repair in the kidney immediately after ischemia–reperfusion

O Kwon, S Miller, N Li, A Khan… - … of Histochemistry & …, 2010 - journals.sagepub.com
In ischemic acute kidney injury, renal blood flow is decreased. We have previously shown
that reperfused, transplanted kidneys exhibited ischemic injury to vascular endothelium and …

Mesenchymal stem cells contribute to the renal repair of acute tubular epithelial injury

MB Herrera, B Bussolati, S Bruno… - International …, 2004 - spandidos-publications.com
Acute renal failure (ARF) is a common disease with high morbidity and mortality. Recovery
from ARF is dependent on the replacement of necrotic tubular cells with functional tubular …

Mesenchymal stem cells in renal ischemia-reperfusion injury: biological and therapeutic perspectives

H Hu, C Zou - Current stem cell research & therapy, 2017 - ingentaconnect.com
Acute renal failure (ARF) is a syndrome of abrupt decline in renal function induced by a
number of different insults. In clinic, the common etiology for ARF is ischemia-reperfusion …

Skeletal muscle‐derived stem/progenitor cells: a potential strategy for the treatment of acute kidney injury

E Pavyde, R Maciulaitis, M Mauricas… - Stem cells …, 2016 - Wiley Online Library
Skeletal muscle‐derived stem/progenitor cells (MDSPCs) have been thoroughly
investigated and already used in preclinical studies. However, therapeutic potential of …