[HTML][HTML] Definition of treatment-resistant depression–Asia Pacific perspectives

CH Ng, T Kato, C Han, G Wang, M Trivedi… - Journal of affective …, 2019 - Elsevier
Background The lack of uniformity in the definition of treatment resistant depression (TRD)
within the Asia-Pacific (APAC) region may have implications for patient management. We …

[HTML][HTML] Real-world evidence from a European cohort study of patients with treatment resistant depression: treatment patterns and clinical outcomes

K Heerlein, G Perugi, C Otte, T Frodl… - Journal of Affective …, 2021 - Elsevier
Background Treatment resistant depression (TRD) characterizes a subgroup of 10–30% of
patients with major depressive disorder, and is associated with considerable morbidity and …

The burden and the challenge of treatment-resistant depression.

C Touloumis - Psychiatrike= Psychiatriki, 2021 - europepmc.org
Treatment resistant depression (TRD) is a serious public health problem. It is estimated that
around 20-40% of patients with a major depressive episode (whether monopolar or bipolar) …

Management of treatment-resistant depression: challenges and strategies

D Voineskos, ZJ Daskalakis… - … disease and treatment, 2020 - Taylor & Francis
Abstract Treatment-resistant depression (TRD) is a subset of Major Depressive Disorder
which does not respond to traditional and first-line therapeutic options. There are several …

Staging methods for treatment resistant depression. A systematic review

HG Ruhé, G van Rooijen, J Spijker… - Journal of affective …, 2012 - Elsevier
BACKGROUND: Treatment resistant depressant (TRD) is classified in different staging
models, but these are not used routinely. We aimed to identify staging models for TRD and …

Issues in treatment-resistant depression

MB Keller - Journal of Clinical Psychiatry, 2005 - psychiatrist.com
Major depressive disorder is a debilitating disease that imposes significant social and
economic burdens not only on patients but also on society. Although various treatment …

Treatment-resistant depression in Poland—epidemiology and treatment

P Gałecki, J Samochowiec, M Mikułowska… - Journal of clinical …, 2022 - mdpi.com
(1) Background: Major depressive disorder (MDD) is one of the most prevalent psychiatric
disorders worldwide. Although several antidepressant drugs have been developed, up to …

Treatment‐resistant major depressive disorder: Canadian expert consensus on definition and assessment

YE Rybak, KSP Lai, R Ramasubbu… - Depression and …, 2021 - Wiley Online Library
Background Treatment‐resistant depression (TRD) is a debilitating chronic mental illness
that confers increased morbidity and mortality, decreases the quality of life, impairs …

[HTML][HTML] The assessment of resistance to antidepressant treatment: Rationale for the Antidepressant Treatment History Form: Short Form (ATHF-SF)

HA Sackeim, ST Aaronson, MT Bunker… - Journal of psychiatric …, 2019 - Elsevier
There is considerable diversity in how treatment-resistant depression (TRD) is defined.
However, every definition incorporates the concept that patients with TRD have not …

Genetic and clinical characteristics of treatment-resistant depression using primary care records in two UK cohorts

C Fabbri, SP Hagenaars, C John, AT Williams… - Molecular …, 2021 - nature.com
Abstract Treatment-resistant depression (TRD) is a major contributor to the disability caused
by major depressive disorder (MDD). Primary care electronic health records provide an …