The neurotoxic effects of l-aspartate were evaluated in rat cerebellar granule cell cultures.
Acute (15 min) exposure to l-aspartate produced a time-dependent, delayed degeneration of …

In primary cultures of mouse cerebral cortex neurons, sulphur‐containing excitatory amino
acids (SAAs; namely, L‐cysteine sulphinate, L‐cysteate, L‐homocysteine sulphinate, L …

L‐aspartate neurotoxicity was quantitatively characterized in murine cortical cell cultures.
Five‐minute exposure to 30 μM–3 mM L‐aspartate resulted in concentration‐dependent …

In slices of developing rat cerebellum, a 30-min application of the excitatory amino acid
receptor agonist, N-methyl-d-aspartate (NMDA), led to the necrosis of differentiating granule …

Cysteine (CYS) is a non-essential amino acid which elicits excitotoxic properties via the N-
methyl-D-aspartate (NMDA) subtype of the glutamate receptor. CYS levels are known to be …

Abstract SKF 10,047 (N-allylnormetazocine) was found to be neuroprotective against
glutamate-induced excitotoxicity in our model system of energy-stressed neurons which …

In addition to the excitatory role played by the amino acid transmitters glutamate and
aspartate in the central nervous system, their sulfur-containing analogues homocysteic acid …

Excitotoxic amino acids contain two acidic groups, but cysteine represents an exception to
this rule. The hypothesis that cysteine toxicity is mediated by the oxidized and diacidic …

Using microspectrofluorimetry and the calcium-sensitive dye fura-2, we examined the effect
of excitatory amino acids on [Ca2+] i in single striatal neurons in vitro. N-methyl-D-aspartic …

Primary cultures of cerebral cortical neurons and single-cell imaging of intracellular free
Ca2+ concentration ([Ca2+] i) with the ratiometric dye fura-2 were used to assess excitatory …