This study was performed to compare the vigor and phenotype of virus-specific CD4+ and
CD8+ T-cell responses in patients with different virologic and clinical outcomes after …

Increasing evidence in recent years has suggested that B cells act as a crucial regulator in
autoimmune diseases. However, little is known about their role in autoimmune hepatitis …

B7-DC, one of the recently described B7 family members, has the capacity to inhibit T cell
responses via engagement of the immunoreceptor tyrosine-based inhibitory motif …

ABSTRACT A majority of patients infected with hepatitis C virus (HCV) do not sustain an
effective T-cell response, and viremia persists. The mechanism leading to failure of the HCV …

CD56+ T cells are abundant in liver and play an important role in defense against viral
infections. However, the role of CD56+ T cells in control of hepatitis C virus (HCV) infection …

We monitored expression of PD-1 (a mediator of T-cell exhaustion and viral persistence) on
hepatitis C virus (HCV)-specific CD8+ and CD4+ T cells from blood and liver during acute …

B7-H1 is a recently identified B7 family member that, along with one of its receptors,
programmed death-1 (PD-1), has been involved in multiple immunopathologic scenarios …

The interaction between the host immune response and infected hepatocytes plays a central
role in the pathogenesis of hepatitis C virus (HCV). The lack of a suitable animal or in vitro …

Hepatitis C virus (HCV) is remarkably efficient at evading host immunity to establish chronic
infection. During chronic HCV infection, interleukin‐12 (IL‐12) produced by monocytes …

Abstract CD4+ CD25+ FoxP3+ regulatory T cells (Tregs) are increased in patients with
chronic hepatitis C, which may contribute to the sustained suppression of hepatitis C virus …