Cytotoxicity of major tanshinones isolated from Danshen (Salvia miltiorrhiza) on HepG2 cells in relation to glutathione perturbation

WYW Lee, LCM Chiu, JHK Yeung - Food and chemical toxicology, 2008 - Elsevier
Tanshinones are abietane type-diterpene quinones isolated from the roots of Radix Salvia
miltiorrhiza (Danshen), a well-known traditional Chinese medicine in the treatment of …

Dihydrotanshinone I inhibits ovarian cancer cell proliferation and migration by transcriptional repression of PIK3CA gene

X Wang, X Xu, G Jiang, C Zhang, L Liu… - Journal of Cellular …, 2020 - Wiley Online Library
Dihydrotanshinone I (DHTS), extracted from Salvia miltiorrhiza, was found to be the most
effective compound of tanshen extracts against cancer cells in our previous studies …

Tanshinone IIA down-regulates the protein expression of ErbB-2 and up-regulates TNF-α in colon cancer cells in vitro and in vivo

CC Su, YH Lin - International Journal of Molecular …, 2008 - spandidos-publications.com
Abstract Tanshinone IIA (Tan-IIA) was isolated from Salviae Miltiorrhizae Radix. Our
previous studies showed that Tan-IIA induced apoptosis in human colon cancer colo 205 …

[HTML][HTML] Flowers and Leaves Extracts of Stachys palustris L. Exhibit Stronger Anti-Proliferative, Antioxidant, Anti-Diabetic, and Anti-Obesity Potencies than Stems and …

S Lachowicz-Wiśniewska, A Pratap-Singh, I Kapusta… - Pharmaceuticals, 2022 - mdpi.com
The present work aims to assess the biological potential of polyphenolic compounds in
different parts (flowers, leaves, stems, and roots) of Stachys palustris L. Towards secondary …

[PDF][PDF] Anticancer and antioxidative activities of Stephania venosa

P Leewanich, A Worachartcheewan… - European Journal of …, 2011 - researchgate.net
Stephania venosa, known to be a rich source of isoquinoline alkaloids, is used as the Thai
folk remedy for cancer treatment. Herein, ethanol and water extracts of the S. venosa were …

Cytotoxic effect of hydroalcoholic extract of Stachys setifera on MCF-7 human breast cancer cell line

E Panahi Kokhdan, H Sadeghi… - Armaghane Danesh, 2021 - armaghanj.yums.ac.ir
Background & aim: Breast cancer is the most common cancer among women. Today,
compounds derived from medicinal plants are used in the treatment of various cancers …

[HTML][HTML] Tanshinone IIA can inhibit MiaPaCa‑2 human pancreatic cancer cells by dual blockade of the Ras/Raf/MEK/ERK and PI3K/AKT/mTOR pathways

CC Su - Oncology reports, 2018 - spandidos-publications.com
Abstract Tanshinone IIA (Tan‑IIA; C19H18O3) is derived from Danshen (the roots of Salvia
miltiorrhiza), and has been reported to possess anti‑inflammatory and antioxidant activities …

Tanshinone-IIA-based analogues of imidazole alkaloid act as potent inhibitors to block breast cancer invasion and metastasis in vivo

Q Wu, K Zheng, X Huang, L Li… - Journal of medicinal …, 2018 - ACS Publications
Tanshinone-IIA (Tan-IIA), a primary active component extracted from commonly used
Chinese herbal, Salvia miltiorrhiza (Danshen), is considered as a potential inhibitor against …

Influence of tanshinone IIA on the apoptosis of human esophageal Ec-109 cells

YQ Zhu, BY Wang, F Wu, YK An… - Natural Product …, 2016 - journals.sagepub.com
The induced-apoptosis effect and mechanism of human esophageal cancer Ec-109 cells via
tanshinone IIA was investigated. The Ec-109 cells were cultured in vitro with different …

[HTML][HTML] Dihydrotanshinone I Enhances Cell Adhesion and Inhibits Cell Migration in Osteosarcoma U− 2 OS Cells through CD44 and Chemokine Signaling

L Fan, C Peng, X Zhu, Y Liang, T Xu, P Xu, S Wu - Molecules, 2022 - mdpi.com
In the screening of novel natural products against cancer using an in vitro cancer cell model,
we recently found that tanshinones from a traditional Chinese medicine, the rhizome of …