Traumatic brain injury (TBI) remains one of the leading causes of mortality and morbidity
worldwide in individuals under the age of 45 years, and, despite extensive efforts to develop …

Traumatic brain injury (TBI) is a major contributor to disability and death worldwide, and
manifests in cognitive, behavioral, and motor impairment. Although there have been …

The clinical understanding of traumatic brain injury (TBI) and its manifestations is beginning
to change. Both clinicians and research scientists are recognizing that TBI and related …

Traumatic brain injury (TBI) is one of the leading causes of death and disability in the
industrialised world and remains a major health problem with serious socioeconomic …

The realization of a successful pharmacological treatment for use in severe clinical traumatic
brain injury (TBI) has eluded researchers for at least 3 decades in spite of the fact that …

Traumatic brain injury (TBI) affects 1.6 million Americans annually. The injury severity
impacts the overall outcome and likelihood for survival. Current treatment of acute TBI …

To date, despite very encouraging preclinical results, almost all phase II/III clinical
neuroprotection trials in traumatic brain injury (TBI) have failed to show any consistent …

Background: This review summarizes promising approaches for the treatment of traumatic
brain injury (TBI) that are in either preclinical or clinical trials. Objective: The …

The role of neuroprotection in traumatic brain injury (TBI) is reviewed. Basic research and
experimental investigations have identified many different compounds with potential …

Successful treatment strategies for patients with traumatic brain injury (TBI) remain elusive
despite standardised clinical treatment guidelines, improved understanding of mechanisms …