The role of calcium in capsaicin-induced desensitization in rat cultured dorsal root ganglion neurons
A Cholewinski, GM Burgess, S Bevan - Neuroscience, 1993 - Elsevier
The effects of capsaicin cytosolic Ca 2+ concentration ([Ca 2+] i) were measured in
individual dorsal root ganglion neurons of the rat in culture. Capsaicin produced a rapid …
individual dorsal root ganglion neurons of the rat in culture. Capsaicin produced a rapid …
Inhibition of calcineurin inhibits the desensitization of capsaicin-evoked currents in cultured dorsal root ganglion neurones from adult rats
RJ Docherty, JC Yeats, S Bevan, H Boddeke - Pflügers Archiv, 1996 - Springer
Capsaicin activates a non-specific cation conductance in mammalian sensory neurones. If
capsaicin is applied continuously or repeatedly then there is a progressive decline in …
capsaicin is applied continuously or repeatedly then there is a progressive decline in …
The role of calcium in the desensitization of capsaicin responses in rat dorsal root ganglion neurons
PA Koplas, RL Rosenberg, GS Oxford - Journal of Neuroscience, 1997 - Soc Neuroscience
Capsaicin (Cap) is a pungent extract of the Capsicum pepper family, which activates
nociceptive primary sensory neurons. Inward current and membrane potential responses of …
nociceptive primary sensory neurons. Inward current and membrane potential responses of …
Effects of capsaicin on Ca2+ release from the intracellular Ca2+ stores in the dorsal root ganglion cells of adult rats
SY Eun, SJ Jung, YK Park, J Kwak, SJ Kim… - … and Biophysical Research …, 2001 - Elsevier
We have investigated the effect of capsaicin on Ca2+ release from the intracellular calcium
stores. Intracellular calcium concentration ([Ca2+] i) was measured in rat dorsal root …
stores. Intracellular calcium concentration ([Ca2+] i) was measured in rat dorsal root …
Capsaicin causes prolonged inhibition of voltage-activated calcium currents in adult rat dorsal root ganglion neurons in culture
RJ Docherty, B Robertson, S Bevan - Neuroscience, 1991 - Elsevier
The effect of capsaicin on voltage-activated calcium currents was investigated in
voltageclamped somata of cultured adult rat dorsal root ganglion neurons. About half the …
voltageclamped somata of cultured adult rat dorsal root ganglion neurons. About half the …
The effect of capsaicin on voltage‐gated calcium currents and calcium signals in cultured dorsal root ganglion cells
D Bleakman, JR Brorson… - British journal of …, 1990 - Wiley Online Library
1 The effects of capsaicin on voltage‐gated Ca2+ currents (ICa), and intracellular Ca2+
concentrations ([Ca2+] i) in cultured dorsal root ganglion (DRG) neurones of the rat were …
concentrations ([Ca2+] i) in cultured dorsal root ganglion (DRG) neurones of the rat were …
[HTML][HTML] Multiple capsaicin-induced currents in isolated rat sensory neurons
M Petersen, RH Lamotte, A Klusch, KD Kniffki - Neuroscience, 1996 - Elsevier
The response to capsaicin in functional assays suggests multiple sites of capsaicin action.
This hypothesis is supported by the results of the present patch-clamp study of isolated …
This hypothesis is supported by the results of the present patch-clamp study of isolated …
The mechanism of action of capsaicin on sensory C-type neurons and their axons in vitro
SJ Marsh, CE Stansfeld, DA Brown, R Davey… - Neuroscience, 1987 - Elsevier
The selective excitant and neurotoxic action of capsaicin on vagal sensory neurons in the rat
has been investigated in vitro using three techniques: extracellular recording of compound …
has been investigated in vitro using three techniques: extracellular recording of compound …
Low pH facilitates capsaicin responses in isolated sensory neurons of the rat
M Kress, S Fetzer, PW Reeh, L Vyklicky - Neuroscience letters, 1996 - Elsevier
The effects of capsaicin (CAPS; 30 nM, 300 nM, 3 μM) and acidic solutions (pH 6.6, 6.1, 5.6,
5.1) were studied in dorsal root ganglion (DRG) neurons from adult rats in short term culture …
5.1) were studied in dorsal root ganglion (DRG) neurons from adult rats in short term culture …
Capsaicin-induced ion fluxes in dorsal root ganglion cells in culture
Capsaicin is a pungent pain-producing compound found in plants of the capsicum family; it
exerts excitatory, desensitizing, and toxic effects on a subset of sensory neurons, including …
exerts excitatory, desensitizing, and toxic effects on a subset of sensory neurons, including …